A quorum sensing regulated small volatile molecule reduces acute virulence and promotes chronic infection phenotypes.

A significant number of environmental microorganisms can cause serious, even fatal, acute and chronic infections in humans. The severity and outcome of each type of infection depends on the expression of specific bacterial phenotypes controlled by complex regulatory networks that sense and respond t...

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Bibliographic Details
Main Authors: Meenu Kesarwani, Ronen Hazan, Jianxin He, Yok-Ai Que, Yiorgos Apidianakis, Biliana Lesic, Gaoping Xiao, Valérie Dekimpe, Sylvain Milot, Eric Deziel, François Lépine, Laurence G Rahme
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3150319?pdf=render