Identifying direct targets of transcription factor Rfx2 that coordinate ciliogenesis and cell movement
Recently, using the frog Xenopus laevis as a model system, we showed that the transcription factor Rfx2 coordinates many genes involved in ciliogenesis and cell movement in multiciliated cells (Chung et al., 2014). To our knowledge, it was the first paper to utilize the genomic resources, including...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2014-12-01
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| Series: | Genomics Data |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213596014000488 |
| _version_ | 1818308540850241536 |
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| author | Taejoon Kwon Mei-I Chung Rakhi Gupta Julie C. Baker John B. Wallingford Edward M. Marcotte |
| author_facet | Taejoon Kwon Mei-I Chung Rakhi Gupta Julie C. Baker John B. Wallingford Edward M. Marcotte |
| author_sort | Taejoon Kwon |
| collection | DOAJ |
| description | Recently, using the frog Xenopus laevis as a model system, we showed that the transcription factor Rfx2 coordinates many genes involved in ciliogenesis and cell movement in multiciliated cells (Chung et al., 2014). To our knowledge, it was the first paper to utilize the genomic resources, including genome sequences and interim gene annotations, from the ongoing X. laevis genome project. For researchers who are interested in the application of genomics and systems biology approaches in Xenopus studies, here we provide additional details about our dataset (NCBI GEO accession number GSE50593) and describe how we analyzed RNA-seq and ChIP-seq data to identify direct targets of Rfx2. |
| first_indexed | 2024-12-13T07:15:54Z |
| format | Article |
| id | doaj.art-c53eee1d7f934b31ab864d472c7ae07e |
| institution | Directory Open Access Journal |
| issn | 2213-5960 |
| language | English |
| last_indexed | 2024-12-13T07:15:54Z |
| publishDate | 2014-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Genomics Data |
| spelling | doaj.art-c53eee1d7f934b31ab864d472c7ae07e2022-12-21T23:55:34ZengElsevierGenomics Data2213-59602014-12-012C19219410.1016/j.gdata.2014.06.015Identifying direct targets of transcription factor Rfx2 that coordinate ciliogenesis and cell movementTaejoon Kwon0Mei-I Chung1Rakhi Gupta2Julie C. Baker3John B. Wallingford4Edward M. Marcotte5Department of Molecular Biosciences, University of Texas at Austin, United StatesDepartment of Molecular Biosciences, University of Texas at Austin, United StatesDepartment of Genetics, Stanford University, United StatesDepartment of Genetics, Stanford University, United StatesDepartment of Molecular Biosciences, University of Texas at Austin, United StatesDepartment of Molecular Biosciences, University of Texas at Austin, United StatesRecently, using the frog Xenopus laevis as a model system, we showed that the transcription factor Rfx2 coordinates many genes involved in ciliogenesis and cell movement in multiciliated cells (Chung et al., 2014). To our knowledge, it was the first paper to utilize the genomic resources, including genome sequences and interim gene annotations, from the ongoing X. laevis genome project. For researchers who are interested in the application of genomics and systems biology approaches in Xenopus studies, here we provide additional details about our dataset (NCBI GEO accession number GSE50593) and describe how we analyzed RNA-seq and ChIP-seq data to identify direct targets of Rfx2.http://www.sciencedirect.com/science/article/pii/S2213596014000488Xenopus laevisRfx2Ciliogenesis |
| spellingShingle | Taejoon Kwon Mei-I Chung Rakhi Gupta Julie C. Baker John B. Wallingford Edward M. Marcotte Identifying direct targets of transcription factor Rfx2 that coordinate ciliogenesis and cell movement Genomics Data Xenopus laevis Rfx2 Ciliogenesis |
| title | Identifying direct targets of transcription factor Rfx2 that coordinate ciliogenesis and cell movement |
| title_full | Identifying direct targets of transcription factor Rfx2 that coordinate ciliogenesis and cell movement |
| title_fullStr | Identifying direct targets of transcription factor Rfx2 that coordinate ciliogenesis and cell movement |
| title_full_unstemmed | Identifying direct targets of transcription factor Rfx2 that coordinate ciliogenesis and cell movement |
| title_short | Identifying direct targets of transcription factor Rfx2 that coordinate ciliogenesis and cell movement |
| title_sort | identifying direct targets of transcription factor rfx2 that coordinate ciliogenesis and cell movement |
| topic | Xenopus laevis Rfx2 Ciliogenesis |
| url | http://www.sciencedirect.com/science/article/pii/S2213596014000488 |
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