Ocular Rosacea microBiome Study (ORBS)—sub-microbial versus antibiotic dosing of doxycycline versus placebo in treatment of symptomatic ocular rosacea: study protocol for a parallel-arm randomized clinical trial

Ocular Rosacea microBiome Study (ORBS)—sub-microbial versus antibiotic dosing of doxycycline versus placebo in treatment of symptomatic ocular rosacea: study protocol for a parallel-arm randomized clinical trial

Abstract Background Ocular rosacea is common and is often managed with long-term antibiotic treatment. Doxycycline is the most commonly selected antibiotic for the treatment of rosacea. As there is no established standard of care treatment dose for rosacea, prescribed doses of doxycycline vary widel...

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Bibliographic Details
Main Authors: Hamidah Mahmud, Jeremy D. Keenan, John Gonzales, Julie Schallhorn, Matilda Chan, Benjamin Arnold, Victoria Cavallino, Thomas M. Lietman, Thuy Doan, Gerami D. Seitzman
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Trials
Subjects:
Ocular rosacea
Microbiome
Doxycycline
Sub-microbial
Antimicrobial resistance
Online Access:https://doi.org/10.1186/s13063-022-06948-9

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