The Efficacy and Safety of Socks Containing Urea for the Treatment of Xerosis in Diabetic Feet
Objective: To investigate the efficacy and safety of urea-containing socks for the treatment of xerosis of the foot in diabetic patients. Material and Methods: After baseline foot examination, the participants wore urea-containing socks which contains 20 mL of urea solution on both feet for 2 hours....
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| Format: | Article |
| Language: | English |
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Prince of Songkla University
2014-08-01
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| Series: | Journal of Health Science and Medical Research (JHSMR) |
| Subjects: | |
| Online Access: | https://www.jhsmr.org/index.php/jhsmr/article/view/222 |
| _version_ | 1818135710252662784 |
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| author | Pornanong Aramwit Surawej Numhom |
| author_facet | Pornanong Aramwit Surawej Numhom |
| author_sort | Pornanong Aramwit |
| collection | DOAJ |
| description | Objective: To investigate the efficacy and safety of urea-containing socks for the treatment of xerosis of the foot in diabetic patients.
Material and Methods: After baseline foot examination, the participants wore urea-containing socks which contains 20 mL of urea solution on both feet for 2 hours. Repeated foot examination was performed by a physician after one week. Participants were given a satisfaction survey at the end of the study.
Results: Eighteen participants enrolled in the study. One withdrew from the study due to minor side effects (swelling of skin but no peeling after the use of urea-containing socks for 3 days). The results from 17 participants indicated that the number of xerosis of feet was reduced compared to baseline (1.09±0.85 vs 1.61±0.58, p=0.036). Moreover, the severity of xerosis was reduced significantly after using urea-containing socks compared to baseline (1.77±2.13 vs 2.46±2.37, p=0.000). Only 10 participants (58.82%) with high degree of xerosis at the beginning of the study needed further treatment. The rest of the participants need no further treatment. Mild side effects were experienced in 12 participants (70.59%) including burning sensation, itching, rash or numbness. No participants experienced serious side effects.
Conclusion: Short term observation indicates that urea-containing socks are safe and can be used as alternative treatment for xerosis of the foot in diabetic patients with high efficacy in mild xerosis. However, patients with high degree of xerosis may need repeated treatment or use other treatments concomitantly. |
| first_indexed | 2024-12-11T09:28:50Z |
| format | Article |
| id | doaj.art-c54743c28bd0430aa08c77021292ac26 |
| institution | Directory Open Access Journal |
| issn | 2586-9981 2630-0559 |
| language | English |
| last_indexed | 2024-12-11T09:28:50Z |
| publishDate | 2014-08-01 |
| publisher | Prince of Songkla University |
| record_format | Article |
| series | Journal of Health Science and Medical Research (JHSMR) |
| spelling | doaj.art-c54743c28bd0430aa08c77021292ac262022-12-22T01:13:05ZengPrince of Songkla UniversityJournal of Health Science and Medical Research (JHSMR)2586-99812630-05592014-08-01324249258236The Efficacy and Safety of Socks Containing Urea for the Treatment of Xerosis in Diabetic FeetPornanong Aramwit0Surawej Numhom1Bioactive Resources for Innovative Clinical Applications Research Unit, Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Pathum Wan, Bangkok, 10330,Department of Surgery, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Ratchatewi, Bangkok, 10400,Objective: To investigate the efficacy and safety of urea-containing socks for the treatment of xerosis of the foot in diabetic patients. Material and Methods: After baseline foot examination, the participants wore urea-containing socks which contains 20 mL of urea solution on both feet for 2 hours. Repeated foot examination was performed by a physician after one week. Participants were given a satisfaction survey at the end of the study. Results: Eighteen participants enrolled in the study. One withdrew from the study due to minor side effects (swelling of skin but no peeling after the use of urea-containing socks for 3 days). The results from 17 participants indicated that the number of xerosis of feet was reduced compared to baseline (1.09±0.85 vs 1.61±0.58, p=0.036). Moreover, the severity of xerosis was reduced significantly after using urea-containing socks compared to baseline (1.77±2.13 vs 2.46±2.37, p=0.000). Only 10 participants (58.82%) with high degree of xerosis at the beginning of the study needed further treatment. The rest of the participants need no further treatment. Mild side effects were experienced in 12 participants (70.59%) including burning sensation, itching, rash or numbness. No participants experienced serious side effects. Conclusion: Short term observation indicates that urea-containing socks are safe and can be used as alternative treatment for xerosis of the foot in diabetic patients with high efficacy in mild xerosis. However, patients with high degree of xerosis may need repeated treatment or use other treatments concomitantly.https://www.jhsmr.org/index.php/jhsmr/article/view/222diabeticfootureaxerosis |
| spellingShingle | Pornanong Aramwit Surawej Numhom The Efficacy and Safety of Socks Containing Urea for the Treatment of Xerosis in Diabetic Feet Journal of Health Science and Medical Research (JHSMR) diabetic foot urea xerosis |
| title | The Efficacy and Safety of Socks Containing Urea for the Treatment of Xerosis in Diabetic Feet |
| title_full | The Efficacy and Safety of Socks Containing Urea for the Treatment of Xerosis in Diabetic Feet |
| title_fullStr | The Efficacy and Safety of Socks Containing Urea for the Treatment of Xerosis in Diabetic Feet |
| title_full_unstemmed | The Efficacy and Safety of Socks Containing Urea for the Treatment of Xerosis in Diabetic Feet |
| title_short | The Efficacy and Safety of Socks Containing Urea for the Treatment of Xerosis in Diabetic Feet |
| title_sort | efficacy and safety of socks containing urea for the treatment of xerosis in diabetic feet |
| topic | diabetic foot urea xerosis |
| url | https://www.jhsmr.org/index.php/jhsmr/article/view/222 |
| work_keys_str_mv | AT pornanongaramwit theefficacyandsafetyofsockscontainingureaforthetreatmentofxerosisindiabeticfeet AT surawejnumhom theefficacyandsafetyofsockscontainingureaforthetreatmentofxerosisindiabeticfeet AT pornanongaramwit efficacyandsafetyofsockscontainingureaforthetreatmentofxerosisindiabeticfeet AT surawejnumhom efficacyandsafetyofsockscontainingureaforthetreatmentofxerosisindiabeticfeet |