Simultaneous oral administration of Salmonella Infantis and S. Typhimurium in chicks
Abstract Background To confirm the hypothesis that Salmonella enterica subspecies enterica serovar (S.) Infantis has higher basic reproductive rates in chicks compared with other Salmonella serovars, 1-day-old specific-pathogen-free chicks (n = 8) were challenged simultaneously with S. Infantis and...
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| Format: | Article |
| Language: | English |
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BMC
2017-08-01
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| Series: | Irish Veterinary Journal |
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| Online Access: | http://link.springer.com/article/10.1186/s13620-017-0105-x |
| _version_ | 1828742414210170880 |
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| author | Koichi Murakami Eriko Maeda-Mitani Daisuke Onozuka Tamie Noda Nobuyuki Sera Hirokazu Kimura Shuji Fujimoto Satoshi Murakami |
| author_facet | Koichi Murakami Eriko Maeda-Mitani Daisuke Onozuka Tamie Noda Nobuyuki Sera Hirokazu Kimura Shuji Fujimoto Satoshi Murakami |
| author_sort | Koichi Murakami |
| collection | DOAJ |
| description | Abstract Background To confirm the hypothesis that Salmonella enterica subspecies enterica serovar (S.) Infantis has higher basic reproductive rates in chicks compared with other Salmonella serovars, 1-day-old specific-pathogen-free chicks (n = 8) were challenged simultaneously with S. Infantis and S. Typhimurium per os. Challenged chicks (Group A) were then housed with non-infected chicks (Group B, n = 4) for 6 days (from 2 to 8 days of age). Group B birds were then housed with other non-infected birds (Group C, n = 4), which were then transferred to cages containing a further group of untreated chicks (Group D, n = 2). A control group consisting of four non-infected chicks was used for comparison. All chickens were humanely sacrificed at 18 days of age, and Salmonella from bowel and liver samples were enumerated. Results Both serovars were isolated from all groups except the control group. S. Typhimurium was isolated at a greater frequency than S. Infantis from the bowel samples of chicks from Groups B, C and D, while no differences in colonisation rates were observed between the two serovars in liver samples from Groups B, C and D. S. Typhimurium, but not S. Infantis, was immunohistochemically detected in the lamina propria of the cecum and rectum in five birds of Group A. Despite the competitive administration, neither of the two serovars completely excluded the other, and no differences were observed in basic reproductive rates between the two serovars. Conclusions These findings, together with data from previous studies, suggest that the initial quantitative domination of S. Infantis in chicken flocks may explain why this serovar is predominant in broiler chickens. |
| first_indexed | 2024-04-13T01:19:07Z |
| format | Article |
| id | doaj.art-c54c269b5c9c41b497f98427efbdfe84 |
| institution | Directory Open Access Journal |
| issn | 2046-0481 |
| language | English |
| last_indexed | 2024-04-13T01:19:07Z |
| publishDate | 2017-08-01 |
| publisher | BMC |
| record_format | Article |
| series | Irish Veterinary Journal |
| spelling | doaj.art-c54c269b5c9c41b497f98427efbdfe842022-12-22T03:08:50ZengBMCIrish Veterinary Journal2046-04812017-08-017011610.1186/s13620-017-0105-xSimultaneous oral administration of Salmonella Infantis and S. Typhimurium in chicksKoichi Murakami0Eriko Maeda-Mitani1Daisuke Onozuka2Tamie Noda3Nobuyuki Sera4Hirokazu Kimura5Shuji Fujimoto6Satoshi Murakami7Infectious Disease Surveillance Center, National Institute of Infectious DiseasesFukuoka Institute of Health and Environmental SciencesDepartment of Health Care Administration and Management, Kyushu University Graduate School of Medical SciencesFukuoka Institute of Health and Environmental SciencesFukuoka Institute of Health and Environmental SciencesInfectious Disease Surveillance Center, National Institute of Infectious DiseasesDepartment of Health Sciences, Faculty of Medical Sciences, Kyushu UniversityDepartment of Animal Science, Tokyo University of AgricultureAbstract Background To confirm the hypothesis that Salmonella enterica subspecies enterica serovar (S.) Infantis has higher basic reproductive rates in chicks compared with other Salmonella serovars, 1-day-old specific-pathogen-free chicks (n = 8) were challenged simultaneously with S. Infantis and S. Typhimurium per os. Challenged chicks (Group A) were then housed with non-infected chicks (Group B, n = 4) for 6 days (from 2 to 8 days of age). Group B birds were then housed with other non-infected birds (Group C, n = 4), which were then transferred to cages containing a further group of untreated chicks (Group D, n = 2). A control group consisting of four non-infected chicks was used for comparison. All chickens were humanely sacrificed at 18 days of age, and Salmonella from bowel and liver samples were enumerated. Results Both serovars were isolated from all groups except the control group. S. Typhimurium was isolated at a greater frequency than S. Infantis from the bowel samples of chicks from Groups B, C and D, while no differences in colonisation rates were observed between the two serovars in liver samples from Groups B, C and D. S. Typhimurium, but not S. Infantis, was immunohistochemically detected in the lamina propria of the cecum and rectum in five birds of Group A. Despite the competitive administration, neither of the two serovars completely excluded the other, and no differences were observed in basic reproductive rates between the two serovars. Conclusions These findings, together with data from previous studies, suggest that the initial quantitative domination of S. Infantis in chicken flocks may explain why this serovar is predominant in broiler chickens.http://link.springer.com/article/10.1186/s13620-017-0105-xSalmonella infantisSalmonella typhimuriumChickenBasic reproductive rateOral administrationChick bowel |
| spellingShingle | Koichi Murakami Eriko Maeda-Mitani Daisuke Onozuka Tamie Noda Nobuyuki Sera Hirokazu Kimura Shuji Fujimoto Satoshi Murakami Simultaneous oral administration of Salmonella Infantis and S. Typhimurium in chicks Irish Veterinary Journal Salmonella infantis Salmonella typhimurium Chicken Basic reproductive rate Oral administration Chick bowel |
| title | Simultaneous oral administration of Salmonella Infantis and S. Typhimurium in chicks |
| title_full | Simultaneous oral administration of Salmonella Infantis and S. Typhimurium in chicks |
| title_fullStr | Simultaneous oral administration of Salmonella Infantis and S. Typhimurium in chicks |
| title_full_unstemmed | Simultaneous oral administration of Salmonella Infantis and S. Typhimurium in chicks |
| title_short | Simultaneous oral administration of Salmonella Infantis and S. Typhimurium in chicks |
| title_sort | simultaneous oral administration of salmonella infantis and s typhimurium in chicks |
| topic | Salmonella infantis Salmonella typhimurium Chicken Basic reproductive rate Oral administration Chick bowel |
| url | http://link.springer.com/article/10.1186/s13620-017-0105-x |
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