Seroprevalence of malaria in inhabitants of the urban zone of Antananarivo, Madagascar
<p>Abstract</p> <p>Background</p> <p>Antananarivo, the capital of Madagascar, is located at an altitude of over 1,200 m. The environment at this altitude is not particularly favourable to malaria transmission, but malaria nonetheless remains a major public health proble...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2006-11-01
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| Series: | Malaria Journal |
| Online Access: | http://www.malariajournal.com/content/5/1/106 |
| _version_ | 1811296523902779392 |
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| author | Rakotomanana Fanjasoa Randremanana Rindra Jolivet Laurence Rakotomalala Emma Razakandrainibe Romy Domarle Olivier Ramarokoto Charles Soares Jean-Louis Ariey Frédéric |
| author_facet | Rakotomanana Fanjasoa Randremanana Rindra Jolivet Laurence Rakotomalala Emma Razakandrainibe Romy Domarle Olivier Ramarokoto Charles Soares Jean-Louis Ariey Frédéric |
| author_sort | Rakotomanana Fanjasoa |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Antananarivo, the capital of Madagascar, is located at an altitude of over 1,200 m. The environment at this altitude is not particularly favourable to malaria transmission, but malaria nonetheless remains a major public health problem. The aim of this study was to evaluate exposure to malaria in the urban population of Antananarivo, by measuring the specific seroprevalence of <it>Plasmodium falciparum</it>.</p> <p>Methods</p> <p>Serological studies specific for <it>P. falciparum </it>were carried out with an indirect fluorescent antibody test (IFAT). In a representative population of Antananarivo, 1,059 healthy volunteers were interviewed and serum samples were taken.</p> <p>Results</p> <p>The seroprevalence of IgG+IgA+IgM was 56.1% and that of IgM was 5.9%. The major risk factor associated with a positive IgG+IgA+IgM IFAT was travel outside Antananarivo, whether in the central highlands or on the coast. The abundance of rice fields in certain urban districts was not associated with a higher seroprevalence.</p> <p>Conclusion</p> <p>Malaria transmission levels are low in Antananarivo, but seroprevalence is high. Humans come into contact with the parasite primarily when travelling outside the city. Further studies are required to identify indigenous risk factors and intra-city variations more clearly.</p> |
| first_indexed | 2024-04-13T05:49:56Z |
| format | Article |
| id | doaj.art-c54c851456f6442ca140748197e5cc67 |
| institution | Directory Open Access Journal |
| issn | 1475-2875 |
| language | English |
| last_indexed | 2024-04-13T05:49:56Z |
| publishDate | 2006-11-01 |
| publisher | BMC |
| record_format | Article |
| series | Malaria Journal |
| spelling | doaj.art-c54c851456f6442ca140748197e5cc672022-12-22T02:59:49ZengBMCMalaria Journal1475-28752006-11-015110610.1186/1475-2875-5-106Seroprevalence of malaria in inhabitants of the urban zone of Antananarivo, MadagascarRakotomanana FanjasoaRandremanana RindraJolivet LaurenceRakotomalala EmmaRazakandrainibe RomyDomarle OlivierRamarokoto CharlesSoares Jean-LouisAriey Frédéric<p>Abstract</p> <p>Background</p> <p>Antananarivo, the capital of Madagascar, is located at an altitude of over 1,200 m. The environment at this altitude is not particularly favourable to malaria transmission, but malaria nonetheless remains a major public health problem. The aim of this study was to evaluate exposure to malaria in the urban population of Antananarivo, by measuring the specific seroprevalence of <it>Plasmodium falciparum</it>.</p> <p>Methods</p> <p>Serological studies specific for <it>P. falciparum </it>were carried out with an indirect fluorescent antibody test (IFAT). In a representative population of Antananarivo, 1,059 healthy volunteers were interviewed and serum samples were taken.</p> <p>Results</p> <p>The seroprevalence of IgG+IgA+IgM was 56.1% and that of IgM was 5.9%. The major risk factor associated with a positive IgG+IgA+IgM IFAT was travel outside Antananarivo, whether in the central highlands or on the coast. The abundance of rice fields in certain urban districts was not associated with a higher seroprevalence.</p> <p>Conclusion</p> <p>Malaria transmission levels are low in Antananarivo, but seroprevalence is high. Humans come into contact with the parasite primarily when travelling outside the city. Further studies are required to identify indigenous risk factors and intra-city variations more clearly.</p>http://www.malariajournal.com/content/5/1/106 |
| spellingShingle | Rakotomanana Fanjasoa Randremanana Rindra Jolivet Laurence Rakotomalala Emma Razakandrainibe Romy Domarle Olivier Ramarokoto Charles Soares Jean-Louis Ariey Frédéric Seroprevalence of malaria in inhabitants of the urban zone of Antananarivo, Madagascar Malaria Journal |
| title | Seroprevalence of malaria in inhabitants of the urban zone of Antananarivo, Madagascar |
| title_full | Seroprevalence of malaria in inhabitants of the urban zone of Antananarivo, Madagascar |
| title_fullStr | Seroprevalence of malaria in inhabitants of the urban zone of Antananarivo, Madagascar |
| title_full_unstemmed | Seroprevalence of malaria in inhabitants of the urban zone of Antananarivo, Madagascar |
| title_short | Seroprevalence of malaria in inhabitants of the urban zone of Antananarivo, Madagascar |
| title_sort | seroprevalence of malaria in inhabitants of the urban zone of antananarivo madagascar |
| url | http://www.malariajournal.com/content/5/1/106 |
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