Quantification of cell edge velocities and traction forces reveals distinct motility modules during cell spreading.

Quantification of cell edge velocities and traction forces reveals distinct motility modules during cell spreading.

Actin-based cell motility and force generation are central to immune response, tissue development, and cancer metastasis, and understanding actin cytoskeleton regulation is a major goal of cell biologists. Cell spreading is a commonly used model system for motility experiments -- spreading fibroblas...

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Bibliographic Details
Main Authors: Benjamin J Dubin-Thaler, Jake M Hofman, Yunfei Cai, Harry Xenias, Ingrid Spielman, Anna V Shneidman, Lawrence A David, Hans-Günther Döbereiner, Chris H Wiggins, Michael P Sheetz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2581916?pdf=render

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