Pilomatrixoma causing irreversible peripheral eyebrow shedding: A case report
Pilomatrixomas are benign tumors derived from hair stromal cells; however, their exact etiology is unknown. A 31-year-old woman presented with a subcutaneous mass located precisely above the left eyebrow, with shedding of eyebrow hair around the mass, and the shedding area gradually expanded. Surgic...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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KeAi Communications Co. Ltd.
2023-03-01
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| Series: | Chinese Journal of Plastic and Reconstructive Surgery |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2096691123000018 |
| _version_ | 1797844354350448640 |
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| author | Zeren Shen Fei Cheng Yanqin Dai Yijia Yu Lulu Ye Jinghong Xu |
| author_facet | Zeren Shen Fei Cheng Yanqin Dai Yijia Yu Lulu Ye Jinghong Xu |
| author_sort | Zeren Shen |
| collection | DOAJ |
| description | Pilomatrixomas are benign tumors derived from hair stromal cells; however, their exact etiology is unknown. A 31-year-old woman presented with a subcutaneous mass located precisely above the left eyebrow, with shedding of eyebrow hair around the mass, and the shedding area gradually expanded. Surgical removal of the mass failed to prevent eyebrow loss, and the entire left eyebrow shed 6 months postoperatively. Pathology and histology of the biopsy specimen revealed a pilomatrixoma comprising basaloid cells and ghost cells, with basaloid cells expressing high bcl-2 levels. Instead of apoptosis, the emergence and growth of pilomatrixoma-induced microinflammation around the hair follicles of the eyebrow may lead to eyebrow loss. |
| first_indexed | 2024-04-09T17:20:56Z |
| format | Article |
| id | doaj.art-c550d8e536ac4025b6854d647553f1f0 |
| institution | Directory Open Access Journal |
| issn | 2096-6911 |
| language | English |
| last_indexed | 2024-04-09T17:20:56Z |
| publishDate | 2023-03-01 |
| publisher | KeAi Communications Co. Ltd. |
| record_format | Article |
| series | Chinese Journal of Plastic and Reconstructive Surgery |
| spelling | doaj.art-c550d8e536ac4025b6854d647553f1f02023-04-19T04:22:31ZengKeAi Communications Co. Ltd.Chinese Journal of Plastic and Reconstructive Surgery2096-69112023-03-01513032Pilomatrixoma causing irreversible peripheral eyebrow shedding: A case reportZeren Shen0Fei Cheng1Yanqin Dai2Yijia Yu3Lulu Ye4Jinghong Xu5Department of Plastic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, Zhejiang, ChinaDepartment of Pathology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, Zhejiang, ChinaDepartment of Plastic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, Zhejiang, ChinaDepartment of Plastic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, Zhejiang, ChinaDepartment of Plastic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, Zhejiang, ChinaDepartment of Plastic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, Zhejiang, China; Corresponding author. Department of Plastic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, 79 Qingchun Road, Hangzhou 310003, Zhejiang, China.Pilomatrixomas are benign tumors derived from hair stromal cells; however, their exact etiology is unknown. A 31-year-old woman presented with a subcutaneous mass located precisely above the left eyebrow, with shedding of eyebrow hair around the mass, and the shedding area gradually expanded. Surgical removal of the mass failed to prevent eyebrow loss, and the entire left eyebrow shed 6 months postoperatively. Pathology and histology of the biopsy specimen revealed a pilomatrixoma comprising basaloid cells and ghost cells, with basaloid cells expressing high bcl-2 levels. Instead of apoptosis, the emergence and growth of pilomatrixoma-induced microinflammation around the hair follicles of the eyebrow may lead to eyebrow loss.http://www.sciencedirect.com/science/article/pii/S2096691123000018PilomatrixomaEyebrow sheddingMicroinflammation |
| spellingShingle | Zeren Shen Fei Cheng Yanqin Dai Yijia Yu Lulu Ye Jinghong Xu Pilomatrixoma causing irreversible peripheral eyebrow shedding: A case report Chinese Journal of Plastic and Reconstructive Surgery Pilomatrixoma Eyebrow shedding Microinflammation |
| title | Pilomatrixoma causing irreversible peripheral eyebrow shedding: A case report |
| title_full | Pilomatrixoma causing irreversible peripheral eyebrow shedding: A case report |
| title_fullStr | Pilomatrixoma causing irreversible peripheral eyebrow shedding: A case report |
| title_full_unstemmed | Pilomatrixoma causing irreversible peripheral eyebrow shedding: A case report |
| title_short | Pilomatrixoma causing irreversible peripheral eyebrow shedding: A case report |
| title_sort | pilomatrixoma causing irreversible peripheral eyebrow shedding a case report |
| topic | Pilomatrixoma Eyebrow shedding Microinflammation |
| url | http://www.sciencedirect.com/science/article/pii/S2096691123000018 |
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