A case of pancreatic head cancer with Trousseau’s syndrome treated with radical resection and anticoagulant therapy
Abstract Background The primary disease of Trousseau’s syndrome is often highly advanced cancer, and treatment of the primary disease after cerebral infarction is often difficult. We herein report a case of pancreatic head cancer with Trousseau’s syndrome treated with radical resection and anticoagu...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2023-01-01
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| Series: | Surgical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40792-023-01585-z |
| _version_ | 1828063650589442048 |
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| author | Takumi Kitahama Shimpei Otsuka Teiichi Sugiura Ryo Ashida Katsuhisa Ohgi Mihoko Yamada Katsuhiko Uesaka |
| author_facet | Takumi Kitahama Shimpei Otsuka Teiichi Sugiura Ryo Ashida Katsuhisa Ohgi Mihoko Yamada Katsuhiko Uesaka |
| author_sort | Takumi Kitahama |
| collection | DOAJ |
| description | Abstract Background The primary disease of Trousseau’s syndrome is often highly advanced cancer, and treatment of the primary disease after cerebral infarction is often difficult. We herein report a case of pancreatic head cancer with Trousseau’s syndrome treated with radical resection and anticoagulant therapy. Case presentation A 78-year-old man was admitted with dizziness and diagnosed with cerebral infarction. Abdominal contrast-enhanced computed tomography for a thorough checkup indicated borderline resectable pancreatic head cancer. Radical resection after neoadjuvant chemotherapy (NAC; gemcitabine plus nab-paclitaxel) was scheduled. During the second course of NAC, multiple cerebral infarctions recurred, and the patient was diagnosed with Trousseau’s syndrome. Continuous intravenous infusion of heparin was started for cerebral infarction. Since it was impossible to continue NAC and there was no worsening of imaging findings, radical resection was planned. Thereafter, he underwent pancreatoduodenectomy with superior mesenteric vein resection. The patient progressed well and was discharged on the 19th day after surgery. He continued subcutaneous injection of heparin at home and is alive without recurrence of cancer or cerebral infarction at more than 21 months after surgery. Conclusion Surgical treatment may be an option for pancreatic cancer with Trousseau’s syndrome under favorable conditions. |
| first_indexed | 2024-04-10T22:46:22Z |
| format | Article |
| id | doaj.art-c551b2f32a474de5a08ccab15a972917 |
| institution | Directory Open Access Journal |
| issn | 2198-7793 |
| language | English |
| last_indexed | 2024-04-10T22:46:22Z |
| publishDate | 2023-01-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Surgical Case Reports |
| spelling | doaj.art-c551b2f32a474de5a08ccab15a9729172023-01-15T12:20:06ZengSpringerOpenSurgical Case Reports2198-77932023-01-01911710.1186/s40792-023-01585-zA case of pancreatic head cancer with Trousseau’s syndrome treated with radical resection and anticoagulant therapyTakumi Kitahama0Shimpei Otsuka1Teiichi Sugiura2Ryo Ashida3Katsuhisa Ohgi4Mihoko Yamada5Katsuhiko Uesaka6Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer CenterDivision of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer CenterDivision of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer CenterDivision of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer CenterDivision of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer CenterDivision of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer CenterDivision of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer CenterAbstract Background The primary disease of Trousseau’s syndrome is often highly advanced cancer, and treatment of the primary disease after cerebral infarction is often difficult. We herein report a case of pancreatic head cancer with Trousseau’s syndrome treated with radical resection and anticoagulant therapy. Case presentation A 78-year-old man was admitted with dizziness and diagnosed with cerebral infarction. Abdominal contrast-enhanced computed tomography for a thorough checkup indicated borderline resectable pancreatic head cancer. Radical resection after neoadjuvant chemotherapy (NAC; gemcitabine plus nab-paclitaxel) was scheduled. During the second course of NAC, multiple cerebral infarctions recurred, and the patient was diagnosed with Trousseau’s syndrome. Continuous intravenous infusion of heparin was started for cerebral infarction. Since it was impossible to continue NAC and there was no worsening of imaging findings, radical resection was planned. Thereafter, he underwent pancreatoduodenectomy with superior mesenteric vein resection. The patient progressed well and was discharged on the 19th day after surgery. He continued subcutaneous injection of heparin at home and is alive without recurrence of cancer or cerebral infarction at more than 21 months after surgery. Conclusion Surgical treatment may be an option for pancreatic cancer with Trousseau’s syndrome under favorable conditions.https://doi.org/10.1186/s40792-023-01585-zPancreatic ductal adenocarcinomaTrousseau’s syndrome |
| spellingShingle | Takumi Kitahama Shimpei Otsuka Teiichi Sugiura Ryo Ashida Katsuhisa Ohgi Mihoko Yamada Katsuhiko Uesaka A case of pancreatic head cancer with Trousseau’s syndrome treated with radical resection and anticoagulant therapy Surgical Case Reports Pancreatic ductal adenocarcinoma Trousseau’s syndrome |
| title | A case of pancreatic head cancer with Trousseau’s syndrome treated with radical resection and anticoagulant therapy |
| title_full | A case of pancreatic head cancer with Trousseau’s syndrome treated with radical resection and anticoagulant therapy |
| title_fullStr | A case of pancreatic head cancer with Trousseau’s syndrome treated with radical resection and anticoagulant therapy |
| title_full_unstemmed | A case of pancreatic head cancer with Trousseau’s syndrome treated with radical resection and anticoagulant therapy |
| title_short | A case of pancreatic head cancer with Trousseau’s syndrome treated with radical resection and anticoagulant therapy |
| title_sort | case of pancreatic head cancer with trousseau s syndrome treated with radical resection and anticoagulant therapy |
| topic | Pancreatic ductal adenocarcinoma Trousseau’s syndrome |
| url | https://doi.org/10.1186/s40792-023-01585-z |
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