A radiological footprint equivalent to liquefactive necrosis observed in the course of disappearing liver metastases in rectal cancer: A case report and review of the literature

A 72-year-old female diagnosed with rectal cancer treated with a surgical procedure was reported. As 3 liver metastases (LMs) appeared in multidetector CT, adjuvant chemotherapy using Bevacizumab combined with modified FOLFOX-6 was completed. LMs were changed to cystic lesions during the follow-up p...

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Main Authors: Kazuki Yamada, MD, Yasuhiko Fujita, MD, PhD, Teruyoshi Amagai, MD, PhD
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Radiology Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1930043322002746
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author Kazuki Yamada, MD
Yasuhiko Fujita, MD, PhD
Teruyoshi Amagai, MD, PhD
author_facet Kazuki Yamada, MD
Yasuhiko Fujita, MD, PhD
Teruyoshi Amagai, MD, PhD
author_sort Kazuki Yamada, MD
collection DOAJ
description A 72-year-old female diagnosed with rectal cancer treated with a surgical procedure was reported. As 3 liver metastases (LMs) appeared in multidetector CT, adjuvant chemotherapy using Bevacizumab combined with modified FOLFOX-6 was completed. LMs were changed to cystic lesions during the follow-up period, consistent with liquefactive necrosis. These cystic lesions that appeared in the course of disappearing LMs (DLMs) were identified by CT as homogeneous low signal intensity in hepatocyte specific Gd-enhanced MRI. This might be pathognomonic radiological footprint equivalent to liquefactive necrosis observed in the process of DLM and must be carefully followed in the course of radiological complete response. The radiological changing findings of LMs to cystic changes, high sensitivity of detecting DLM, and limitations of Gd-MRI might be meaningful to clinicians.
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spelling doaj.art-c55432e307db43cab77a936b0b644a7a2022-12-22T00:39:25ZengElsevierRadiology Case Reports1930-04332022-07-0117725832588A radiological footprint equivalent to liquefactive necrosis observed in the course of disappearing liver metastases in rectal cancer: A case report and review of the literatureKazuki Yamada, MD0Yasuhiko Fujita, MD, PhD1Teruyoshi Amagai, MD, PhD2Department of Medicine, Tokunoshima Tokushukai General Hospital, Kagoshima, JapanDepartment of Medicine, Tokunoshima Tokushukai General Hospital, Kagoshima, JapanDepartment of Medicine, Tokunoshima Tokushukai General Hospital, Kagoshima, Japan; Faculty of Health Care Sciences, Department of Clinical Engineering, Jikei University of Health Care Sciences, 1-2-8, Miyahara, Yodogawa-Ku, Osaka, 532-0003, Japan; Corresponding author.A 72-year-old female diagnosed with rectal cancer treated with a surgical procedure was reported. As 3 liver metastases (LMs) appeared in multidetector CT, adjuvant chemotherapy using Bevacizumab combined with modified FOLFOX-6 was completed. LMs were changed to cystic lesions during the follow-up period, consistent with liquefactive necrosis. These cystic lesions that appeared in the course of disappearing LMs (DLMs) were identified by CT as homogeneous low signal intensity in hepatocyte specific Gd-enhanced MRI. This might be pathognomonic radiological footprint equivalent to liquefactive necrosis observed in the process of DLM and must be carefully followed in the course of radiological complete response. The radiological changing findings of LMs to cystic changes, high sensitivity of detecting DLM, and limitations of Gd-MRI might be meaningful to clinicians.http://www.sciencedirect.com/science/article/pii/S1930043322002746Colorectal cancerDisappearing liver metastases (DLM)Liquefactive necrosisMagnetic resonance imaging (MRI)EOB MRIRadiological complete response
spellingShingle Kazuki Yamada, MD
Yasuhiko Fujita, MD, PhD
Teruyoshi Amagai, MD, PhD
A radiological footprint equivalent to liquefactive necrosis observed in the course of disappearing liver metastases in rectal cancer: A case report and review of the literature
Radiology Case Reports
Colorectal cancer
Disappearing liver metastases (DLM)
Liquefactive necrosis
Magnetic resonance imaging (MRI)
EOB MRI
Radiological complete response
title A radiological footprint equivalent to liquefactive necrosis observed in the course of disappearing liver metastases in rectal cancer: A case report and review of the literature
title_full A radiological footprint equivalent to liquefactive necrosis observed in the course of disappearing liver metastases in rectal cancer: A case report and review of the literature
title_fullStr A radiological footprint equivalent to liquefactive necrosis observed in the course of disappearing liver metastases in rectal cancer: A case report and review of the literature
title_full_unstemmed A radiological footprint equivalent to liquefactive necrosis observed in the course of disappearing liver metastases in rectal cancer: A case report and review of the literature
title_short A radiological footprint equivalent to liquefactive necrosis observed in the course of disappearing liver metastases in rectal cancer: A case report and review of the literature
title_sort radiological footprint equivalent to liquefactive necrosis observed in the course of disappearing liver metastases in rectal cancer a case report and review of the literature
topic Colorectal cancer
Disappearing liver metastases (DLM)
Liquefactive necrosis
Magnetic resonance imaging (MRI)
EOB MRI
Radiological complete response
url http://www.sciencedirect.com/science/article/pii/S1930043322002746
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