Increased connectivity of hiPSC-derived neural networks in multiphase granular hydrogel scaffolds

Increased connectivity of hiPSC-derived neural networks in multiphase granular hydrogel scaffolds

To reflect human development, it is critical to create a substrate that can support long-term cell survival, differentiation, and maturation. Hydrogels are promising materials for 3D cultures. However, a bulk structure consisting of dense polymer networks often leads to suboptimal microenvironments...

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Bibliographic Details
Main Authors: Chia-Chen Hsu, Julian H. George, Sharlayne Waller, Cyril Besnard, David A Nagel, Eric J Hill, Michael D. Coleman, Alexander M. Korsunsky, Zhanfeng Cui, Hua Ye
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-03-01
Series:Bioactive Materials
Subjects:
Microgel
Hydrogel
Hyaluronan
iPSC
Neural tissue engineering
3D printing
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X21003418

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