Scanning Tunneling Microscopy of Biological Structures: An Elusive Goal for Many Years

Scanning tunneling microscopy (STM) is a technique that can be used to directly observe individual biomolecules at near-molecular scale. Within this framework, STM is of crucial significance because of its role in the structural analysis, the understanding the imaging formation, and the development...

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Main Authors: Andrés Rodríguez-Galván, Flavio F. Contreras-Torres
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Nanomaterials
Subjects:
Online Access:https://www.mdpi.com/2079-4991/12/17/3013
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author Andrés Rodríguez-Galván
Flavio F. Contreras-Torres
author_facet Andrés Rodríguez-Galván
Flavio F. Contreras-Torres
author_sort Andrés Rodríguez-Galván
collection DOAJ
description Scanning tunneling microscopy (STM) is a technique that can be used to directly observe individual biomolecules at near-molecular scale. Within this framework, STM is of crucial significance because of its role in the structural analysis, the understanding the imaging formation, and the development of relative techniques. Four decades after its invention, it is pertinent to ask how much of the early dream has come true. In this study, we aim to overview different analyses for DNA, lipids, proteins, and carbohydrates. The relevance of STM imaging is exhibited as an opportunity to assist measurements and biomolecular identification in nanobiotechnology, nanomedicine, biosensing, and other cutting-edge applications. We believe STM research is still an entire science research ecosystem for joining several areas of expertise towards a goal settlement that has been elusive for many years.
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spelling doaj.art-c555d5e20f9a4b3282dc59191594f8342023-11-23T13:49:24ZengMDPI AGNanomaterials2079-49912022-08-011217301310.3390/nano12173013Scanning Tunneling Microscopy of Biological Structures: An Elusive Goal for Many YearsAndrés Rodríguez-Galván0Flavio F. Contreras-Torres1Carrera de Biología, Unidad de Biomedicina, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla 54090, Edo. Mex., MexicoTecnologico de Monterrey, The Institute for Obesity Research, Monterrey 64849, NL, MexicoScanning tunneling microscopy (STM) is a technique that can be used to directly observe individual biomolecules at near-molecular scale. Within this framework, STM is of crucial significance because of its role in the structural analysis, the understanding the imaging formation, and the development of relative techniques. Four decades after its invention, it is pertinent to ask how much of the early dream has come true. In this study, we aim to overview different analyses for DNA, lipids, proteins, and carbohydrates. The relevance of STM imaging is exhibited as an opportunity to assist measurements and biomolecular identification in nanobiotechnology, nanomedicine, biosensing, and other cutting-edge applications. We believe STM research is still an entire science research ecosystem for joining several areas of expertise towards a goal settlement that has been elusive for many years.https://www.mdpi.com/2079-4991/12/17/3013scanning tunneling microscopynucleic acidscarbohydratesproteinslipids
spellingShingle Andrés Rodríguez-Galván
Flavio F. Contreras-Torres
Scanning Tunneling Microscopy of Biological Structures: An Elusive Goal for Many Years
Nanomaterials
scanning tunneling microscopy
nucleic acids
carbohydrates
proteins
lipids
title Scanning Tunneling Microscopy of Biological Structures: An Elusive Goal for Many Years
title_full Scanning Tunneling Microscopy of Biological Structures: An Elusive Goal for Many Years
title_fullStr Scanning Tunneling Microscopy of Biological Structures: An Elusive Goal for Many Years
title_full_unstemmed Scanning Tunneling Microscopy of Biological Structures: An Elusive Goal for Many Years
title_short Scanning Tunneling Microscopy of Biological Structures: An Elusive Goal for Many Years
title_sort scanning tunneling microscopy of biological structures an elusive goal for many years
topic scanning tunneling microscopy
nucleic acids
carbohydrates
proteins
lipids
url https://www.mdpi.com/2079-4991/12/17/3013
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