Mitoxantrone induces natural killer cell maturation in patients with secondary progressive multiple sclerosis.

Mitoxantrone induces natural killer cell maturation in patients with secondary progressive multiple sclerosis.

Mitoxantrone is one of the few drugs approved for the treatment of progressive multiple sclerosis (MS). However, the prolonged use of this potent immunosuppressive agent is limited by the appearance of severe side effects. Apart from its general cytotoxic effect, the mode of action of mitoxantrone o...

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Bibliographic Details
Main Authors: Coralie Chanvillard, Jason M Millward, Marta Lozano, Isabell Hamann, Friedemann Paul, Frauke Zipp, Jan Dörr, Carmen Infante-Duarte
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22768101/?tool=EBI

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