Histologic evaluation of activity and chronicity of lupus nephritis and its clinical significance

The National Institutes of Health (NIH) lupus nephritis activity and chronicity indices, which comprise six activity scores and four chronicity scores, have a long development history. The 2018 revised International Society of Nephrology/Renal Pathology Society classification for lupus nephritis ado...

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Main Authors: Sung-Eun Choi, Agnes B. Fogo, Beom Jin Lim
Format: Article
Language:English
Published: The Korean Society of Nephrology 2023-03-01
Series:Kidney Research and Clinical Practice
Subjects:
Online Access:http://krcp-ksn.org/upload/pdf/j-krcp-22-083.pdf
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author Sung-Eun Choi
Agnes B. Fogo
Beom Jin Lim
author_facet Sung-Eun Choi
Agnes B. Fogo
Beom Jin Lim
author_sort Sung-Eun Choi
collection DOAJ
description The National Institutes of Health (NIH) lupus nephritis activity and chronicity indices, which comprise six activity scores and four chronicity scores, have a long development history. The 2018 revised International Society of Nephrology/Renal Pathology Society classification for lupus nephritis adopted the most recent NIH indices to replace subclasses A, C, and A/C. Although an evidence-based approach should further evaluate the clinical significance of the modified NIH indices, recent validation studies demonstrated that the modified chronicity indices have a strong correlation with kidney outcome of lupus nephritis.
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spelling doaj.art-c5569ef8ca1a45a3b157fb3870a6fe762023-05-23T06:13:23ZengThe Korean Society of NephrologyKidney Research and Clinical Practice2211-91322211-91402023-03-0142216617310.23876/j.krcp.22.0836169Histologic evaluation of activity and chronicity of lupus nephritis and its clinical significanceSung-Eun Choi0Agnes B. Fogo1Beom Jin Lim2 Department of Pathology, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Republic of Korea Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA Department of Pathology, Yonsei University College of Medicine, Seoul, Republic of KoreaThe National Institutes of Health (NIH) lupus nephritis activity and chronicity indices, which comprise six activity scores and four chronicity scores, have a long development history. The 2018 revised International Society of Nephrology/Renal Pathology Society classification for lupus nephritis adopted the most recent NIH indices to replace subclasses A, C, and A/C. Although an evidence-based approach should further evaluate the clinical significance of the modified NIH indices, recent validation studies demonstrated that the modified chronicity indices have a strong correlation with kidney outcome of lupus nephritis.http://krcp-ksn.org/upload/pdf/j-krcp-22-083.pdfbiopsylupus nephritisprognosistreatment outcome
spellingShingle Sung-Eun Choi
Agnes B. Fogo
Beom Jin Lim
Histologic evaluation of activity and chronicity of lupus nephritis and its clinical significance
Kidney Research and Clinical Practice
biopsy
lupus nephritis
prognosis
treatment outcome
title Histologic evaluation of activity and chronicity of lupus nephritis and its clinical significance
title_full Histologic evaluation of activity and chronicity of lupus nephritis and its clinical significance
title_fullStr Histologic evaluation of activity and chronicity of lupus nephritis and its clinical significance
title_full_unstemmed Histologic evaluation of activity and chronicity of lupus nephritis and its clinical significance
title_short Histologic evaluation of activity and chronicity of lupus nephritis and its clinical significance
title_sort histologic evaluation of activity and chronicity of lupus nephritis and its clinical significance
topic biopsy
lupus nephritis
prognosis
treatment outcome
url http://krcp-ksn.org/upload/pdf/j-krcp-22-083.pdf
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