Histologic evaluation of activity and chronicity of lupus nephritis and its clinical significance
The National Institutes of Health (NIH) lupus nephritis activity and chronicity indices, which comprise six activity scores and four chronicity scores, have a long development history. The 2018 revised International Society of Nephrology/Renal Pathology Society classification for lupus nephritis ado...
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Format: | Article |
Language: | English |
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The Korean Society of Nephrology
2023-03-01
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Series: | Kidney Research and Clinical Practice |
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Online Access: | http://krcp-ksn.org/upload/pdf/j-krcp-22-083.pdf |
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author | Sung-Eun Choi Agnes B. Fogo Beom Jin Lim |
author_facet | Sung-Eun Choi Agnes B. Fogo Beom Jin Lim |
author_sort | Sung-Eun Choi |
collection | DOAJ |
description | The National Institutes of Health (NIH) lupus nephritis activity and chronicity indices, which comprise six activity scores and four chronicity scores, have a long development history. The 2018 revised International Society of Nephrology/Renal Pathology Society classification for lupus nephritis adopted the most recent NIH indices to replace subclasses A, C, and A/C. Although an evidence-based approach should further evaluate the clinical significance of the modified NIH indices, recent validation studies demonstrated that the modified chronicity indices have a strong correlation with kidney outcome of lupus nephritis. |
first_indexed | 2024-03-13T10:00:08Z |
format | Article |
id | doaj.art-c5569ef8ca1a45a3b157fb3870a6fe76 |
institution | Directory Open Access Journal |
issn | 2211-9132 2211-9140 |
language | English |
last_indexed | 2024-03-13T10:00:08Z |
publishDate | 2023-03-01 |
publisher | The Korean Society of Nephrology |
record_format | Article |
series | Kidney Research and Clinical Practice |
spelling | doaj.art-c5569ef8ca1a45a3b157fb3870a6fe762023-05-23T06:13:23ZengThe Korean Society of NephrologyKidney Research and Clinical Practice2211-91322211-91402023-03-0142216617310.23876/j.krcp.22.0836169Histologic evaluation of activity and chronicity of lupus nephritis and its clinical significanceSung-Eun Choi0Agnes B. Fogo1Beom Jin Lim2 Department of Pathology, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Republic of Korea Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA Department of Pathology, Yonsei University College of Medicine, Seoul, Republic of KoreaThe National Institutes of Health (NIH) lupus nephritis activity and chronicity indices, which comprise six activity scores and four chronicity scores, have a long development history. The 2018 revised International Society of Nephrology/Renal Pathology Society classification for lupus nephritis adopted the most recent NIH indices to replace subclasses A, C, and A/C. Although an evidence-based approach should further evaluate the clinical significance of the modified NIH indices, recent validation studies demonstrated that the modified chronicity indices have a strong correlation with kidney outcome of lupus nephritis.http://krcp-ksn.org/upload/pdf/j-krcp-22-083.pdfbiopsylupus nephritisprognosistreatment outcome |
spellingShingle | Sung-Eun Choi Agnes B. Fogo Beom Jin Lim Histologic evaluation of activity and chronicity of lupus nephritis and its clinical significance Kidney Research and Clinical Practice biopsy lupus nephritis prognosis treatment outcome |
title | Histologic evaluation of activity and chronicity of lupus nephritis and its clinical significance |
title_full | Histologic evaluation of activity and chronicity of lupus nephritis and its clinical significance |
title_fullStr | Histologic evaluation of activity and chronicity of lupus nephritis and its clinical significance |
title_full_unstemmed | Histologic evaluation of activity and chronicity of lupus nephritis and its clinical significance |
title_short | Histologic evaluation of activity and chronicity of lupus nephritis and its clinical significance |
title_sort | histologic evaluation of activity and chronicity of lupus nephritis and its clinical significance |
topic | biopsy lupus nephritis prognosis treatment outcome |
url | http://krcp-ksn.org/upload/pdf/j-krcp-22-083.pdf |
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