Hypertension and diabetes synergistically strengthen the association with cataracts
AIM: To examine the relationship between age-related cataracts(ARC)and comorbid hypertension and diabetes. <p>METHODS: We analyzed the administrative records of 6 467 patients aged 50 years and older admitted to the ophthalmological department of a tertiary hospital from January 1<sup>st...
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| Format: | Article |
| Language: | English |
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Press of International Journal of Ophthalmology (IJO PRESS)
2020-10-01
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| Series: | Guoji Yanke Zazhi |
| Subjects: | |
| Online Access: | http://ies.ijo.cn/cn_publish/2020/10/202010002.pdf |
| _version_ | 1818097362943344640 |
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| author | Jin-Jin Li Mo-Dong Li Jie Li Xiao Yang Dan Xia Yu Li Wei Wang Fei Yan Jian Zhang |
| author_facet | Jin-Jin Li Mo-Dong Li Jie Li Xiao Yang Dan Xia Yu Li Wei Wang Fei Yan Jian Zhang |
| author_sort | Jin-Jin Li |
| collection | DOAJ |
| description | AIM: To examine the relationship between age-related cataracts(ARC)and comorbid hypertension and diabetes. <p>METHODS: We analyzed the administrative records of 6 467 patients aged 50 years and older admitted to the ophthalmological department of a tertiary hospital from January 1<sup>st</sup>, 2011 to May 20<sup>th</sup>, 2017. With either eye considered, an ARC(<i>n</i>=3 343)was defined as the presence of lens opacity or previous cataract surgery without evidence of trauma, congenital anomalies or using certain medications. Patients admitted to the same department during the same period due to ocular traumas without clinical evidence of cataracts(<i>n</i>=379)were recruited as the cataract-free controls. Unconditional Logistic regressions were ran to obtain the odds ratio(<i>OR</i>)of hypertension and diabetes among ARC patients adjusted for age, sex and health care accessibility.<p>RESULTS: Hypertension was diagnosed in 29.54% of men with any type of cataracts, in 30.12% of men with an ARC, and 10.82% of men of cataract-free controls. Diabetes was diagnosed in 16.64% of men with any type of cataracts, in 16.48% of men with ARC and 4.22% of men of cataract-free controls. Similar patterns were observed among women. After adjusting for age, sex, and health care accessibility, hypertension was weakly \〖<i>OR</i>=1.83(95% <i>CI</i>: 1.23, 2.74)\〗 and diabetes was strongly \〖3.38(1.86, 6.15)\〗 associated with ARCs. The adjusted OR of comorbid hypertension and diabetes among adults with ARC was 18.20(4.38, 75.59). <p>CONCLUSION: Hypertension and diabetes were independently associated with ARC. Hypertension and diabetes, if co-existing, multiplicatively strengthened the association with ARC. |
| first_indexed | 2024-12-10T23:19:19Z |
| format | Article |
| id | doaj.art-c557b8c781e649458912d934ecd0ebf2 |
| institution | Directory Open Access Journal |
| issn | 1672-5123 1672-5123 |
| language | English |
| last_indexed | 2024-12-10T23:19:19Z |
| publishDate | 2020-10-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | Guoji Yanke Zazhi |
| spelling | doaj.art-c557b8c781e649458912d934ecd0ebf22022-12-22T01:29:46ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51231672-51232020-10-0120101673167910.3980/j.issn.1672-5123.2020.10.02Hypertension and diabetes synergistically strengthen the association with cataractsJin-Jin Li0Mo-Dong Li1Jie Li2Xiao Yang3Dan Xia4Yu Li5Wei Wang6Fei Yan7Jian Zhang8Department of Ophthalmology, People's Hospital of Fuyang City, Fuyang 236000, Anhui Province, ChinaDepartment of Ophthalmology, People's Hospital of Fuyang City, Fuyang 236000, Anhui Province, ChinaDepartment of Ophthalmology, People's Hospital of Fuyang City, Fuyang 236000, Anhui Province, ChinaDepartment of Ophthalmology, People's Hospital of Fuyang City, Fuyang 236000, Anhui Province, ChinaDepartment of Ophthalmology, People's Hospital of Fuyang City, Fuyang 236000, Anhui Province, ChinaDepartment of Ophthalmology, People's Hospital of Fuyang City, Fuyang 236000, Anhui Province, ChinaDepartment of Social Medicine, School of Public Health, Fudan University, Shanghai 200433, ChinaDepartment of Social Medicine, School of Public Health, Fudan University, Shanghai 200433, ChinaDepartment of Epidemiology, Jiann-Ping Hsu College of Public Health, Georgia Southern University, Statesboro 30460, GA, USAAIM: To examine the relationship between age-related cataracts(ARC)and comorbid hypertension and diabetes. <p>METHODS: We analyzed the administrative records of 6 467 patients aged 50 years and older admitted to the ophthalmological department of a tertiary hospital from January 1<sup>st</sup>, 2011 to May 20<sup>th</sup>, 2017. With either eye considered, an ARC(<i>n</i>=3 343)was defined as the presence of lens opacity or previous cataract surgery without evidence of trauma, congenital anomalies or using certain medications. Patients admitted to the same department during the same period due to ocular traumas without clinical evidence of cataracts(<i>n</i>=379)were recruited as the cataract-free controls. Unconditional Logistic regressions were ran to obtain the odds ratio(<i>OR</i>)of hypertension and diabetes among ARC patients adjusted for age, sex and health care accessibility.<p>RESULTS: Hypertension was diagnosed in 29.54% of men with any type of cataracts, in 30.12% of men with an ARC, and 10.82% of men of cataract-free controls. Diabetes was diagnosed in 16.64% of men with any type of cataracts, in 16.48% of men with ARC and 4.22% of men of cataract-free controls. Similar patterns were observed among women. After adjusting for age, sex, and health care accessibility, hypertension was weakly \〖<i>OR</i>=1.83(95% <i>CI</i>: 1.23, 2.74)\〗 and diabetes was strongly \〖3.38(1.86, 6.15)\〗 associated with ARCs. The adjusted OR of comorbid hypertension and diabetes among adults with ARC was 18.20(4.38, 75.59). <p>CONCLUSION: Hypertension and diabetes were independently associated with ARC. Hypertension and diabetes, if co-existing, multiplicatively strengthened the association with ARC.http://ies.ijo.cn/cn_publish/2020/10/202010002.pdfcase-controlcataractcomorbiditydiabeteshypertension |
| spellingShingle | Jin-Jin Li Mo-Dong Li Jie Li Xiao Yang Dan Xia Yu Li Wei Wang Fei Yan Jian Zhang Hypertension and diabetes synergistically strengthen the association with cataracts Guoji Yanke Zazhi case-control cataract comorbidity diabetes hypertension |
| title | Hypertension and diabetes synergistically strengthen the association with cataracts |
| title_full | Hypertension and diabetes synergistically strengthen the association with cataracts |
| title_fullStr | Hypertension and diabetes synergistically strengthen the association with cataracts |
| title_full_unstemmed | Hypertension and diabetes synergistically strengthen the association with cataracts |
| title_short | Hypertension and diabetes synergistically strengthen the association with cataracts |
| title_sort | hypertension and diabetes synergistically strengthen the association with cataracts |
| topic | case-control cataract comorbidity diabetes hypertension |
| url | http://ies.ijo.cn/cn_publish/2020/10/202010002.pdf |
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