Comparison of Intraocular Pressure of Both Eyes in Patients with Unilateral Pseudoexfoliation Syndrome

Background & Aims: Pseudoexfoliation syndrome (PXS) is a complex disorder which causes an increase in intraocular pressure (IOP). This study was conducted in order to compare IOP of both eyes of patients with unilateral PXS. Methods: In a cross-sectional study from January 2011 to June 2012, 79...

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Main Authors: Ali Sharif, Hamid Sharifi, Ghodsieh Sharif
Format: Article
Language:English
Published: Kerman University of Medical Sciences 2015-03-01
Series:Journal of Kerman University of Medical Sciences
Subjects:
Online Access:https://jkmu.kmu.ac.ir/article_16120_c4e56f59de3a0c95873456aba5bf4d8a.pdf
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author Ali Sharif
Hamid Sharifi
Ghodsieh Sharif
author_facet Ali Sharif
Hamid Sharifi
Ghodsieh Sharif
author_sort Ali Sharif
collection DOAJ
description Background & Aims: Pseudoexfoliation syndrome (PXS) is a complex disorder which causes an increase in intraocular pressure (IOP). This study was conducted in order to compare IOP of both eyes of patients with unilateral PXS. Methods: In a cross-sectional study from January 2011 to June 2012, 79 patients with unilateral PXS were studied. The patients were examined first with constricted, and then, dilated pupils (after instillation of tropicamide 1%) using slit lamp biomicroscopy. Patients with exfoliative material (XFM) on pupil margin or anterior lens surface of only one eye were included in the study. Age, sex, and intraocular pressures, measured in both involved and noninvolved eyes using Goldman tonometry, were evaluated. Results: IOP of involved eyes was 8-68 (18.78 ± 11.25) mmHg and noninvolved eyes 4-32 (13.67 ± 4.5) mmHg. IOP of noninvolved eyes increased with the increasing of IOP of involved eyes. With increasing age, the amount of IOP of involved eyes increased. However, this relationship was not observed in noninvolved eyes. Conclusion: PXS is a major risk factor for increasing IOP. Since PXS seems to be a systemic disorder, clinically noninvolved eyes may actually be involved or may be at risk to becoming involved. Nevertheless, involved eyes are more susceptible to increased IOP and glaucoma.
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spelling doaj.art-c5598d127b5442339b96ca596d39bd3f2023-07-01T05:24:16ZengKerman University of Medical SciencesJournal of Kerman University of Medical Sciences2008-28432015-03-0122215516516120Comparison of Intraocular Pressure of Both Eyes in Patients with Unilateral Pseudoexfoliation SyndromeAli Sharif0Hamid Sharifi1Ghodsieh Sharif2Associate Professor, Department of Ophthalmology, Afzalipour School of Medicine, Kerman University of Medical Sciences, Kerman, IranAssistant Professor, Department of Food Hygiene and Public Health, School of Veterinary Medicine, Shahid Bahonar University of KermanPediatrician, Department of Pediatrics, Payambar Azam Hospital, Kerman, IranBackground & Aims: Pseudoexfoliation syndrome (PXS) is a complex disorder which causes an increase in intraocular pressure (IOP). This study was conducted in order to compare IOP of both eyes of patients with unilateral PXS. Methods: In a cross-sectional study from January 2011 to June 2012, 79 patients with unilateral PXS were studied. The patients were examined first with constricted, and then, dilated pupils (after instillation of tropicamide 1%) using slit lamp biomicroscopy. Patients with exfoliative material (XFM) on pupil margin or anterior lens surface of only one eye were included in the study. Age, sex, and intraocular pressures, measured in both involved and noninvolved eyes using Goldman tonometry, were evaluated. Results: IOP of involved eyes was 8-68 (18.78 ± 11.25) mmHg and noninvolved eyes 4-32 (13.67 ± 4.5) mmHg. IOP of noninvolved eyes increased with the increasing of IOP of involved eyes. With increasing age, the amount of IOP of involved eyes increased. However, this relationship was not observed in noninvolved eyes. Conclusion: PXS is a major risk factor for increasing IOP. Since PXS seems to be a systemic disorder, clinically noninvolved eyes may actually be involved or may be at risk to becoming involved. Nevertheless, involved eyes are more susceptible to increased IOP and glaucoma.https://jkmu.kmu.ac.ir/article_16120_c4e56f59de3a0c95873456aba5bf4d8a.pdfpseudoexfoliation syndrome (pxs)intraocular pressure (iop)unilateral involvement
spellingShingle Ali Sharif
Hamid Sharifi
Ghodsieh Sharif
Comparison of Intraocular Pressure of Both Eyes in Patients with Unilateral Pseudoexfoliation Syndrome
Journal of Kerman University of Medical Sciences
pseudoexfoliation syndrome (pxs)
intraocular pressure (iop)
unilateral involvement
title Comparison of Intraocular Pressure of Both Eyes in Patients with Unilateral Pseudoexfoliation Syndrome
title_full Comparison of Intraocular Pressure of Both Eyes in Patients with Unilateral Pseudoexfoliation Syndrome
title_fullStr Comparison of Intraocular Pressure of Both Eyes in Patients with Unilateral Pseudoexfoliation Syndrome
title_full_unstemmed Comparison of Intraocular Pressure of Both Eyes in Patients with Unilateral Pseudoexfoliation Syndrome
title_short Comparison of Intraocular Pressure of Both Eyes in Patients with Unilateral Pseudoexfoliation Syndrome
title_sort comparison of intraocular pressure of both eyes in patients with unilateral pseudoexfoliation syndrome
topic pseudoexfoliation syndrome (pxs)
intraocular pressure (iop)
unilateral involvement
url https://jkmu.kmu.ac.ir/article_16120_c4e56f59de3a0c95873456aba5bf4d8a.pdf
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AT ghodsiehsharif comparisonofintraocularpressureofbotheyesinpatientswithunilateralpseudoexfoliationsyndrome