microRNA‐99a‐5p induces cellular senescence in gemcitabine‐resistant bladder cancer by targeting SMARCD1

microRNA‐99a‐5p induces cellular senescence in gemcitabine‐resistant bladder cancer by targeting SMARCD1

Patients with advanced bladder cancer are generally treated with a combination of chemotherapeutics, including gemcitabine, but the effect is limited due to acquisition of drug resistance. Thus, in this study, we investigated the mechanism of gemcitabine resistance. First, gemcitabine‐resistant cell...

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Bibliographic Details
Main Authors: Motoki Tamai, Shuichi Tatarano, Shunsuke Okamura, Wataru Fukumoto, Issei Kawakami, Yoichi Osako, Takashi Sakaguchi, Satoshi Sugita, Masaya Yonemori, Yasutoshi Yamada, Masayuki Nakagawa, Hideki Enokida, Hirofumi Yoshino
Format: Article
Language:English
Published: Wiley 2022-03-01
Series:Molecular Oncology
Subjects:
bladder cancer
cellular senescence
gemcitabine resistance
miR‐99a‐5p
SMARCD1
Online Access:https://doi.org/10.1002/1878-0261.13192

Internet

https://doi.org/10.1002/1878-0261.13192

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