Erythropoietin Mitigates Diabetic Nephropathy by Restoring PINK1/Parkin-Mediated Mitophagy

Erythropoietin Mitigates Diabetic Nephropathy by Restoring PINK1/Parkin-Mediated Mitophagy

Diabetic nephropathy (DN), one of the most detrimental microvascular complications of diabetes, is the leading cause of end-stage renal disease. The pathogenesis of DN is complicated, including hemodynamic changes, inflammatory response, oxidative stress, among others. Recently, many studies have de...

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Bibliographic Details
Main Authors: Xinyao Yi, Wenhui Yan, Tingli Guo, Na Liu, Zhuanzhuan Wang, Jia Shang, Xiaotong Wei, Xin Cui, Yuzhuo Sun, Shuting Ren, Lina Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Pharmacology
Subjects:
EPO
Pink1/parkin
LC3
mitophagy
diabetic nephropathy
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.883057/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.883057/full

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