A mouse model of ATRX deficiency with cognitive deficits and autistic traits

A mouse model of ATRX deficiency with cognitive deficits and autistic traits

Abstract Background ATRX is an ATP-dependent chromatin remodeling protein with essential roles in safeguarding genome integrity and modulating gene expression. Deficiencies in this protein cause ATR-X syndrome, a condition characterized by intellectual disability and an array of developmental abnorm...

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Bibliographic Details
Main Authors: Katherine M. Quesnel, Nicole Martin-Kenny, Nathalie G. Bérubé
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Neurodevelopmental Disorders
Subjects:
Intellectual disability
Autism
ATRX
Sex differences
Mice
Online Access:https://doi.org/10.1186/s11689-023-09508-7

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