Colonic mucosa–associated lymphoid tissue lymphoma: A case report
BackgroundMucosa-associated lymphoid tissue (MALT) lymphoma is a group of extranodal lymphomas that originate from B cells. Primary colonic MALT lymphoma is a rare disease, and there is no consensus on its endoscopic features and standard therapies. It is essential to raise awareness of colonic MALT...
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| Format: | Article |
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Frontiers Media S.A.
2023-04-01
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| Series: | Frontiers in Surgery |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fsurg.2023.1178394/full |
| _version_ | 1797839140483497984 |
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| author | Dan Chen Ding-Fu Zhong Yi Yang Si-Shuang Chen Dong Liu |
| author_facet | Dan Chen Ding-Fu Zhong Yi Yang Si-Shuang Chen Dong Liu |
| author_sort | Dan Chen |
| collection | DOAJ |
| description | BackgroundMucosa-associated lymphoid tissue (MALT) lymphoma is a group of extranodal lymphomas that originate from B cells. Primary colonic MALT lymphoma is a rare disease, and there is no consensus on its endoscopic features and standard therapies. It is essential to raise awareness of colonic MALT lymphoma and choose the appropriate treatment.Case presentationIn this case report, we describe a 0-IIb-type lesion that was found by electronic staining endoscopy and magnifying endoscopy. The patient underwent a definitive diagnostic ESD for diagnosis. The patient was evaluated for lymphoma after diagnostic ESD according to the Lugano 2014 evaluation criteria, which are divided into imaging remission on the basis of CT and/or magnetic resonance imaging (MRI) evaluation and metabolic remission on the basis of PET-CT evaluation. Based on the PET-CT results suggesting increased glucose metabolism in the sigmoid colon, the patient underwent additional surgical treatment. According to the pathological results of the surgery, we found that ESD could treat such lesions, which may provide a new option for colorectal MALT lymphoma.ConclusionThe low incidence of colorectal MALT lymphoma, especially for 0-IIb lesions, which are difficult to detect, requires the use of electronic staining endoscopy to improve the detection rate. The combination with magnification endoscopy can improve the understanding of colorectal MALT lymphoma, which ultimately requires pathological support for diagnosis. According to our experience with the present patient case, ESD seems to be a feasible and economical choice for the treatment of massive colorectal MALT lymphoma. However, the combined application of ESD and another therapy scheme needs further clinical investigation. |
| first_indexed | 2024-04-09T15:53:23Z |
| format | Article |
| id | doaj.art-c55ff4351a7c49e7bedde810758a1c44 |
| institution | Directory Open Access Journal |
| issn | 2296-875X |
| language | English |
| last_indexed | 2024-04-09T15:53:23Z |
| publishDate | 2023-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Surgery |
| spelling | doaj.art-c55ff4351a7c49e7bedde810758a1c442023-04-26T05:29:04ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2023-04-011010.3389/fsurg.2023.11783941178394Colonic mucosa–associated lymphoid tissue lymphoma: A case reportDan Chen0Ding-Fu Zhong1Yi Yang2Si-Shuang Chen3Dong Liu4Department of Gastroenterology, Affiliated Jinhua Hospital of Wenzhou Medical University, Jinhua People's Hospital, Jinhua, ChinaDepartment of Gastroenterology, Affiliated Jinhua Hospital of Wenzhou Medical University, Jinhua People's Hospital, Jinhua, ChinaDepartment of Gastroenterology, Affiliated Jinhua Hospital of Wenzhou Medical University, Jinhua People's Hospital, Jinhua, ChinaDepartment of Pathology, Affiliated Jinhua Hospital of Wenzhou Medical University, Jinhua People's Hospital, Jinhua, ChinaDepartment of Hepatobiliary and Pancreatic Gastroenterology, Affiliated Jinhua Hospital of Wenzhou Medical University, Jinhua People's Hospital, Jinhua, ChinaBackgroundMucosa-associated lymphoid tissue (MALT) lymphoma is a group of extranodal lymphomas that originate from B cells. Primary colonic MALT lymphoma is a rare disease, and there is no consensus on its endoscopic features and standard therapies. It is essential to raise awareness of colonic MALT lymphoma and choose the appropriate treatment.Case presentationIn this case report, we describe a 0-IIb-type lesion that was found by electronic staining endoscopy and magnifying endoscopy. The patient underwent a definitive diagnostic ESD for diagnosis. The patient was evaluated for lymphoma after diagnostic ESD according to the Lugano 2014 evaluation criteria, which are divided into imaging remission on the basis of CT and/or magnetic resonance imaging (MRI) evaluation and metabolic remission on the basis of PET-CT evaluation. Based on the PET-CT results suggesting increased glucose metabolism in the sigmoid colon, the patient underwent additional surgical treatment. According to the pathological results of the surgery, we found that ESD could treat such lesions, which may provide a new option for colorectal MALT lymphoma.ConclusionThe low incidence of colorectal MALT lymphoma, especially for 0-IIb lesions, which are difficult to detect, requires the use of electronic staining endoscopy to improve the detection rate. The combination with magnification endoscopy can improve the understanding of colorectal MALT lymphoma, which ultimately requires pathological support for diagnosis. According to our experience with the present patient case, ESD seems to be a feasible and economical choice for the treatment of massive colorectal MALT lymphoma. However, the combined application of ESD and another therapy scheme needs further clinical investigation.https://www.frontiersin.org/articles/10.3389/fsurg.2023.1178394/fullcolonic mucosa–associated lymphoid tissue lymphomaelectronic staining endoscopypigmented endoscopymagnifying endoscopytreatment |
| spellingShingle | Dan Chen Ding-Fu Zhong Yi Yang Si-Shuang Chen Dong Liu Colonic mucosa–associated lymphoid tissue lymphoma: A case report Frontiers in Surgery colonic mucosa–associated lymphoid tissue lymphoma electronic staining endoscopy pigmented endoscopy magnifying endoscopy treatment |
| title | Colonic mucosa–associated lymphoid tissue lymphoma: A case report |
| title_full | Colonic mucosa–associated lymphoid tissue lymphoma: A case report |
| title_fullStr | Colonic mucosa–associated lymphoid tissue lymphoma: A case report |
| title_full_unstemmed | Colonic mucosa–associated lymphoid tissue lymphoma: A case report |
| title_short | Colonic mucosa–associated lymphoid tissue lymphoma: A case report |
| title_sort | colonic mucosa associated lymphoid tissue lymphoma a case report |
| topic | colonic mucosa–associated lymphoid tissue lymphoma electronic staining endoscopy pigmented endoscopy magnifying endoscopy treatment |
| url | https://www.frontiersin.org/articles/10.3389/fsurg.2023.1178394/full |
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