Development and validation of a dissolution test for empagliflozin in film-coated tablets

Development and validation of a dissolution test for empagliflozin in film-coated tablets

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The present study proposes a validated dissolution method for empagliflozin (EMPA) in film coated tablets. A gradual in vitro dissolution profile for this formulation was obtained using 900 mL of hydrochloric acid 0.01 M at 37 °C ± 0.5 °C as dissolution medium and USP apparatus 2 (paddle) at 50 rpm...

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Bibliographic Details
Main Authors: Joanna Wittckind Manoel, Gabriele Bordignon Primieri, Nadia Maria Volpato, Martin Steppe
Format: Article
Language:English
Published: Universidade Federal do Rio Grande do Sul 2021-12-01
Series:Drug Analytical Research
Online Access:https://seer.ufrgs.br/index.php/dar/article/view/112077

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