A hypothesis about the role of exercise training intensities on bone turn over and muscle-bone cross talk in post-menopausal women: pH influences
PH stress can be caused by menopause, poor nutrition, high protein intake, old age, prolonged strenuous and anaerobic exercise, anemia, diabetes, AIDS, and respiratory diseases. High calcium enters the bloodstream from the bones during the proton buffering due to metabolic acidosis, which the renal...
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| Format: | Article |
| Language: | English |
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JEOCT publisher
2021-06-01
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| Series: | Journal of Exercise & Organ Cross Talk |
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| Online Access: | https://www.jeoct.com/article_130981_66175d1d6f995a20bbdef1fcc104827d.pdf |
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| author | Bakhtiyar Tartibian Zohreh Fathi Hossein Shirvani Fatemeh Mohammadi Ehsan Arabzadeh |
| author_facet | Bakhtiyar Tartibian Zohreh Fathi Hossein Shirvani Fatemeh Mohammadi Ehsan Arabzadeh |
| author_sort | Bakhtiyar Tartibian |
| collection | DOAJ |
| description | PH stress can be caused by menopause, poor nutrition, high protein intake, old age, prolonged strenuous and anaerobic exercise, anemia, diabetes, AIDS, and respiratory diseases. High calcium enters the bloodstream from the bones during the proton buffering due to metabolic acidosis, which the renal system excretes a significant amount of this calcium to eliminate the acidosis condition and regulate body pH. At the bone surface, this increase in hydrogen ions due to metabolic acidosis can destroy osteoblastic and strengthen osteoclast activity, which negative bone turnover and increases the amount of excreted calcium, thus accelerating the progress of osteoporosis. Due to the widespread prevalence of osteoporosis in postmenopausal women and the provision of various therapies such as medication, estrogen therapy, and proper diet, in recent studies, special attention has been paid to the role of endurance and resistance exercise to decrease osteoporosis or prevent the development of this disease. Also exercise training increases irisin secretion from muscle tissue, which this myokine has beneficial effects on other tissues especially on bone. Irisin increases osteocytic survival and production of sclerostin in bone tissue, which is associated with bone remodeling. However, exercise training in some intensity through metabolic mechanisms can increase pH stress and acidosis and may contribute to the development of osteoporosis in postmenopausal women. As a result, the hypothesis of different intensities of exercise and their induced acidosis stimuli in postmenopausal women should be considered. |
| first_indexed | 2024-03-09T03:15:20Z |
| format | Article |
| id | doaj.art-c56646b211a94f4e8518155b41249c41 |
| institution | Directory Open Access Journal |
| issn | 2783-2074 |
| language | English |
| last_indexed | 2024-03-09T03:15:20Z |
| publishDate | 2021-06-01 |
| publisher | JEOCT publisher |
| record_format | Article |
| series | Journal of Exercise & Organ Cross Talk |
| spelling | doaj.art-c56646b211a94f4e8518155b41249c412023-12-03T15:27:26ZengJEOCT publisherJournal of Exercise & Organ Cross Talk2783-20742021-06-01115158https://doi.org/10.22034/JEOCT.2021.286880.1005130981A hypothesis about the role of exercise training intensities on bone turn over and muscle-bone cross talk in post-menopausal women: pH influencesBakhtiyar Tartibian0Zohreh Fathi1Hossein Shirvani2Fatemeh Mohammadi3Ehsan Arabzadeh4Exercise Physiology, Department of Sport Injuries & Corrective Exercises, Faculty of Physical Education & Sport Sciences, Allameh Tabataba'i University, Tehran, IranDepartment of Exercise Physiology, Faculty of Sport Science, University of Mazandaran, Babolsar, IranExercise Physiology Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, IranMaternal, Fetal & Neonatal Research Center, Tehran University of Medical Sciences (TUMS), Tehran, Iran.Exercise Physiology Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, IranPH stress can be caused by menopause, poor nutrition, high protein intake, old age, prolonged strenuous and anaerobic exercise, anemia, diabetes, AIDS, and respiratory diseases. High calcium enters the bloodstream from the bones during the proton buffering due to metabolic acidosis, which the renal system excretes a significant amount of this calcium to eliminate the acidosis condition and regulate body pH. At the bone surface, this increase in hydrogen ions due to metabolic acidosis can destroy osteoblastic and strengthen osteoclast activity, which negative bone turnover and increases the amount of excreted calcium, thus accelerating the progress of osteoporosis. Due to the widespread prevalence of osteoporosis in postmenopausal women and the provision of various therapies such as medication, estrogen therapy, and proper diet, in recent studies, special attention has been paid to the role of endurance and resistance exercise to decrease osteoporosis or prevent the development of this disease. Also exercise training increases irisin secretion from muscle tissue, which this myokine has beneficial effects on other tissues especially on bone. Irisin increases osteocytic survival and production of sclerostin in bone tissue, which is associated with bone remodeling. However, exercise training in some intensity through metabolic mechanisms can increase pH stress and acidosis and may contribute to the development of osteoporosis in postmenopausal women. As a result, the hypothesis of different intensities of exercise and their induced acidosis stimuli in postmenopausal women should be considered.https://www.jeoct.com/article_130981_66175d1d6f995a20bbdef1fcc104827d.pdfmenopauseph stressexercise training intensitiesboneirisin |
| spellingShingle | Bakhtiyar Tartibian Zohreh Fathi Hossein Shirvani Fatemeh Mohammadi Ehsan Arabzadeh A hypothesis about the role of exercise training intensities on bone turn over and muscle-bone cross talk in post-menopausal women: pH influences Journal of Exercise & Organ Cross Talk menopause ph stress exercise training intensities bone irisin |
| title | A hypothesis about the role of exercise training intensities on bone turn over and muscle-bone cross talk in post-menopausal women: pH influences |
| title_full | A hypothesis about the role of exercise training intensities on bone turn over and muscle-bone cross talk in post-menopausal women: pH influences |
| title_fullStr | A hypothesis about the role of exercise training intensities on bone turn over and muscle-bone cross talk in post-menopausal women: pH influences |
| title_full_unstemmed | A hypothesis about the role of exercise training intensities on bone turn over and muscle-bone cross talk in post-menopausal women: pH influences |
| title_short | A hypothesis about the role of exercise training intensities on bone turn over and muscle-bone cross talk in post-menopausal women: pH influences |
| title_sort | hypothesis about the role of exercise training intensities on bone turn over and muscle bone cross talk in post menopausal women ph influences |
| topic | menopause ph stress exercise training intensities bone irisin |
| url | https://www.jeoct.com/article_130981_66175d1d6f995a20bbdef1fcc104827d.pdf |
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