Preliminary insights into high-intensity focused ultrasound ablation for symptomatic uterine fibroids: a first look in Egypt
Abstract Background Uterine fibroids are common gynecological conditions that affect a significant number of women of reproductive age and may necessitate surgical intervention for their removal. However, there is a rising trend toward minimally invasive procedures, such as magnetic resonance-guided...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2024-02-01
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| Series: | The Egyptian Journal of Radiology and Nuclear Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s43055-024-01219-w |
| _version_ | 1827328125515595776 |
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| author | Mohamed Fawzi Safaa ElMandouh Alaa Eid Elbanna Micheal Ezzat Narouz Menna Habib Shrouk Shady Mahmoud Ahmed Said Badr |
| author_facet | Mohamed Fawzi Safaa ElMandouh Alaa Eid Elbanna Micheal Ezzat Narouz Menna Habib Shrouk Shady Mahmoud Ahmed Said Badr |
| author_sort | Mohamed Fawzi |
| collection | DOAJ |
| description | Abstract Background Uterine fibroids are common gynecological conditions that affect a significant number of women of reproductive age and may necessitate surgical intervention for their removal. However, there is a rising trend toward minimally invasive procedures, such as magnetic resonance-guided high-intensity focused ultrasound (MRgHIFU) ablation. This report provides the first experience in Egypt and North Africa on the use of MRgHIFU ablation as a therapeutic option for uterine fibroids. Results This study demonstrates a correlation between post-operative NPV% and symptom improvement. Following a three-month follow-up period, a significant reduction in pain scores and excessive bleeding was observed. Importantly, there was no significant elevation in hemoglobin levels (11.23 ± 2.23 to 11.25 ± 1.71 g/dL) after treatment. Furthermore, the mean non-perfused volume ratio in the treated fibroids was 46 ± 27.3% (SD) among the 20 participants. These findings suggest a favorable therapeutic outcome of MRgHIFU, with no serious adverse effects reported. Conclusion MRgHIFU is a noninvasive therapeutic approach for the treatment of uterine myomas, offering significant benefits in terms of pain reduction and improved quality of life. This particular study represents the pioneering clinical experience of this innovative therapy in Egypt. |
| first_indexed | 2024-03-07T15:13:24Z |
| format | Article |
| id | doaj.art-c5697caed45042dc94ee1ea2c8465a17 |
| institution | Directory Open Access Journal |
| issn | 2090-4762 |
| language | English |
| last_indexed | 2024-03-07T15:13:24Z |
| publishDate | 2024-02-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Journal of Radiology and Nuclear Medicine |
| spelling | doaj.art-c5697caed45042dc94ee1ea2c8465a172024-03-05T18:03:55ZengSpringerOpenThe Egyptian Journal of Radiology and Nuclear Medicine2090-47622024-02-015511810.1186/s43055-024-01219-wPreliminary insights into high-intensity focused ultrasound ablation for symptomatic uterine fibroids: a first look in EgyptMohamed Fawzi0Safaa ElMandouh1Alaa Eid Elbanna2Micheal Ezzat Narouz3Menna Habib4Shrouk Shady Mahmoud5Ahmed Said Badr6Radiology Department, National Hepatology and Tropical Medicine Research InstituteRadiology Department, National Hepatology and Tropical Medicine Research InstituteRadiology Department, National Hepatology and Tropical Medicine Research InstituteRadiology Department, National Hepatology and Tropical Medicine Research InstituteRadiology Department, National Hepatology and Tropical Medicine Research InstituteRadiology Department, National Hepatology and Tropical Medicine Research InstituteRadiology Department, National Hepatology and Tropical Medicine Research InstituteAbstract Background Uterine fibroids are common gynecological conditions that affect a significant number of women of reproductive age and may necessitate surgical intervention for their removal. However, there is a rising trend toward minimally invasive procedures, such as magnetic resonance-guided high-intensity focused ultrasound (MRgHIFU) ablation. This report provides the first experience in Egypt and North Africa on the use of MRgHIFU ablation as a therapeutic option for uterine fibroids. Results This study demonstrates a correlation between post-operative NPV% and symptom improvement. Following a three-month follow-up period, a significant reduction in pain scores and excessive bleeding was observed. Importantly, there was no significant elevation in hemoglobin levels (11.23 ± 2.23 to 11.25 ± 1.71 g/dL) after treatment. Furthermore, the mean non-perfused volume ratio in the treated fibroids was 46 ± 27.3% (SD) among the 20 participants. These findings suggest a favorable therapeutic outcome of MRgHIFU, with no serious adverse effects reported. Conclusion MRgHIFU is a noninvasive therapeutic approach for the treatment of uterine myomas, offering significant benefits in terms of pain reduction and improved quality of life. This particular study represents the pioneering clinical experience of this innovative therapy in Egypt.https://doi.org/10.1186/s43055-024-01219-wUterine fibroidHigh-intensity focused ultrasound (HIFU)Efficacy |
| spellingShingle | Mohamed Fawzi Safaa ElMandouh Alaa Eid Elbanna Micheal Ezzat Narouz Menna Habib Shrouk Shady Mahmoud Ahmed Said Badr Preliminary insights into high-intensity focused ultrasound ablation for symptomatic uterine fibroids: a first look in Egypt The Egyptian Journal of Radiology and Nuclear Medicine Uterine fibroid High-intensity focused ultrasound (HIFU) Efficacy |
| title | Preliminary insights into high-intensity focused ultrasound ablation for symptomatic uterine fibroids: a first look in Egypt |
| title_full | Preliminary insights into high-intensity focused ultrasound ablation for symptomatic uterine fibroids: a first look in Egypt |
| title_fullStr | Preliminary insights into high-intensity focused ultrasound ablation for symptomatic uterine fibroids: a first look in Egypt |
| title_full_unstemmed | Preliminary insights into high-intensity focused ultrasound ablation for symptomatic uterine fibroids: a first look in Egypt |
| title_short | Preliminary insights into high-intensity focused ultrasound ablation for symptomatic uterine fibroids: a first look in Egypt |
| title_sort | preliminary insights into high intensity focused ultrasound ablation for symptomatic uterine fibroids a first look in egypt |
| topic | Uterine fibroid High-intensity focused ultrasound (HIFU) Efficacy |
| url | https://doi.org/10.1186/s43055-024-01219-w |
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