Two years into the Brazilian Reproducibility Initiative: reflections on conducting a large-scale replication of Brazilian biomedical science
Scientists have increasingly recognised that low methodological and analytical rigour combined with publish-or-perish incentives can make the published scientific literature unreliable. As a response to this, large-scale systematic replications of the literature have emerged as a way to assess the p...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Fundação Oswaldo Cruz (FIOCRUZ)
2020-10-01
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| Series: | Memorias do Instituto Oswaldo Cruz |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762020000100853&tlng=en |
| _version_ | 1797757000519516160 |
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| author | Kleber Neves Clarissa FD Carneiro Ana Paula Wasilewska-Sampaio Mariana Abreu Bruna Valério-Gomes Pedro B Tan Olavo B Amaral |
| author_facet | Kleber Neves Clarissa FD Carneiro Ana Paula Wasilewska-Sampaio Mariana Abreu Bruna Valério-Gomes Pedro B Tan Olavo B Amaral |
| author_sort | Kleber Neves |
| collection | DOAJ |
| description | Scientists have increasingly recognised that low methodological and analytical rigour combined with publish-or-perish incentives can make the published scientific literature unreliable. As a response to this, large-scale systematic replications of the literature have emerged as a way to assess the problem empirically. The Brazilian Reproducibility Initiative is one such effort, aimed at estimating the reproducibility of Brazilian biomedical research. Its goal is to perform multicentre replications of a quasi-random sample of at least 60 experiments from Brazilian articles published over a 20-year period, using a set of common laboratory methods. In this article, we describe the challenges of managing a multicentre project with collaborating teams across the country, as well as its successes and failures over the first two years. We end with a brief discussion of the Initiative’s current status and its possible future contributions after the project is concluded in 2021. |
| first_indexed | 2024-03-12T18:09:41Z |
| format | Article |
| id | doaj.art-c56e1d1f56a140e7b8168077c1a96fc5 |
| institution | Directory Open Access Journal |
| issn | 1678-8060 |
| language | English |
| last_indexed | 2024-03-12T18:09:41Z |
| publishDate | 2020-10-01 |
| publisher | Fundação Oswaldo Cruz (FIOCRUZ) |
| record_format | Article |
| series | Memorias do Instituto Oswaldo Cruz |
| spelling | doaj.art-c56e1d1f56a140e7b8168077c1a96fc52023-08-02T09:16:35ZengFundação Oswaldo Cruz (FIOCRUZ)Memorias do Instituto Oswaldo Cruz1678-80602020-10-0111510.1590/0074-02760200328Two years into the Brazilian Reproducibility Initiative: reflections on conducting a large-scale replication of Brazilian biomedical scienceKleber Neveshttps://orcid.org/0000-0001-9519-4909Clarissa FD CarneiroAna Paula Wasilewska-SampaioMariana AbreuBruna Valério-GomesPedro B TanOlavo B AmaralScientists have increasingly recognised that low methodological and analytical rigour combined with publish-or-perish incentives can make the published scientific literature unreliable. As a response to this, large-scale systematic replications of the literature have emerged as a way to assess the problem empirically. The Brazilian Reproducibility Initiative is one such effort, aimed at estimating the reproducibility of Brazilian biomedical research. Its goal is to perform multicentre replications of a quasi-random sample of at least 60 experiments from Brazilian articles published over a 20-year period, using a set of common laboratory methods. In this article, we describe the challenges of managing a multicentre project with collaborating teams across the country, as well as its successes and failures over the first two years. We end with a brief discussion of the Initiative’s current status and its possible future contributions after the project is concluded in 2021.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762020000100853&tlng=enreproducibilitymulticentre studiesreplicationevaluation |
| spellingShingle | Kleber Neves Clarissa FD Carneiro Ana Paula Wasilewska-Sampaio Mariana Abreu Bruna Valério-Gomes Pedro B Tan Olavo B Amaral Two years into the Brazilian Reproducibility Initiative: reflections on conducting a large-scale replication of Brazilian biomedical science Memorias do Instituto Oswaldo Cruz reproducibility multicentre studies replication evaluation |
| title | Two years into the Brazilian Reproducibility Initiative: reflections on conducting a large-scale replication of Brazilian biomedical science |
| title_full | Two years into the Brazilian Reproducibility Initiative: reflections on conducting a large-scale replication of Brazilian biomedical science |
| title_fullStr | Two years into the Brazilian Reproducibility Initiative: reflections on conducting a large-scale replication of Brazilian biomedical science |
| title_full_unstemmed | Two years into the Brazilian Reproducibility Initiative: reflections on conducting a large-scale replication of Brazilian biomedical science |
| title_short | Two years into the Brazilian Reproducibility Initiative: reflections on conducting a large-scale replication of Brazilian biomedical science |
| title_sort | two years into the brazilian reproducibility initiative reflections on conducting a large scale replication of brazilian biomedical science |
| topic | reproducibility multicentre studies replication evaluation |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762020000100853&tlng=en |
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