Is left main percutaneous coronary intervention justified in the presence of concomitant complex coronary artery disease – immediate and remote results – single Bulgarian center experience
Revascularization in patients with severe stenosis of left coronary artery (LCAS) trunk signifi cantly improves their prognosis. Modern clinical studies, registries and meta-analyses have identifi ed percutaneous coronary intervention (PCI) of LCAS as a safe alternative to aorto-coronary bypass (ACB)...
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| Format: | Article |
| Language: | Bulgarian |
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Pensoft Publishers
2020-10-01
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| Series: | Българска кардиология |
| Subjects: | |
| Online Access: | https://journal.bgcardio.org/article/54126/download/pdf/ |
| _version_ | 1797427366475071488 |
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| author | Ivayla Zheleva-Kyuchukova Valeri Gelev |
| author_facet | Ivayla Zheleva-Kyuchukova Valeri Gelev |
| author_sort | Ivayla Zheleva-Kyuchukova |
| collection | DOAJ |
| description | Revascularization in patients with severe stenosis of left coronary artery (LCAS) trunk signifi cantly improves their prognosis. Modern clinical studies, registries and meta-analyses have identifi ed percutaneous coronary intervention (PCI) of LCAS as a safe alternative to aorto-coronary bypass (ACB) in patients with low and intermediate lesion complexity. Aims: To confi rm the safety and effectiveness of PCI and implantation of second generation drug eluting stent (DES) in patients with unprotected LCAS and concomitant complex coronary pathology. Material and Methods: For the period March 2013–October 2018 we performed 225 PCIs of patients with LCAS. 170 of patients who received PCI were divided into 2 groups, according to their SS-1 (ST elevation excluded). We analyzed the major adverse cardio-vascular events (MACE – all-cause mortality, cardiac mortality, stroke and ischemia driven TLR) rate and time-to-fi rst MACE during follow up. Results: 103 patients had SS-I < 32 and 67 patients had SS-I ≥ 32 and their mean age was 67,25 ± 11,03. The median follow-up was 26,6 ± 19,1 months. MACE rate was 12,4% and there was no signifi cance between groups (p = 0,118). Conclusions: PCI of unprotected LCAS has high procedural success rate and good mid-term results, even in pts with complex anatomy. High anatomical complexity of coronary lesions defi ned by SS-I ≥ 32 is not predictive for poor clinical outcome after PCI. |
| first_indexed | 2024-03-09T08:44:14Z |
| format | Article |
| id | doaj.art-c56ff9aca0804abdbc420e157384d71d |
| institution | Directory Open Access Journal |
| issn | 2683-1015 |
| language | Bulgarian |
| last_indexed | 2024-03-09T08:44:14Z |
| publishDate | 2020-10-01 |
| publisher | Pensoft Publishers |
| record_format | Article |
| series | Българска кардиология |
| spelling | doaj.art-c56ff9aca0804abdbc420e157384d71d2023-12-02T16:03:11ZbulPensoft PublishersБългарска кардиология2683-10152020-10-01263435110.3897/bgcardio.26.e5412654126Is left main percutaneous coronary intervention justified in the presence of concomitant complex coronary artery disease – immediate and remote results – single Bulgarian center experienceIvayla Zheleva-Kyuchukova0Valeri Gelev1Acibadem City Clinic Tokuda HospitalAcibadem City Clinic Tokuda HospitalRevascularization in patients with severe stenosis of left coronary artery (LCAS) trunk signifi cantly improves their prognosis. Modern clinical studies, registries and meta-analyses have identifi ed percutaneous coronary intervention (PCI) of LCAS as a safe alternative to aorto-coronary bypass (ACB) in patients with low and intermediate lesion complexity. Aims: To confi rm the safety and effectiveness of PCI and implantation of second generation drug eluting stent (DES) in patients with unprotected LCAS and concomitant complex coronary pathology. Material and Methods: For the period March 2013–October 2018 we performed 225 PCIs of patients with LCAS. 170 of patients who received PCI were divided into 2 groups, according to their SS-1 (ST elevation excluded). We analyzed the major adverse cardio-vascular events (MACE – all-cause mortality, cardiac mortality, stroke and ischemia driven TLR) rate and time-to-fi rst MACE during follow up. Results: 103 patients had SS-I < 32 and 67 patients had SS-I ≥ 32 and their mean age was 67,25 ± 11,03. The median follow-up was 26,6 ± 19,1 months. MACE rate was 12,4% and there was no signifi cance between groups (p = 0,118). Conclusions: PCI of unprotected LCAS has high procedural success rate and good mid-term results, even in pts with complex anatomy. High anatomical complexity of coronary lesions defi ned by SS-I ≥ 32 is not predictive for poor clinical outcome after PCI.https://journal.bgcardio.org/article/54126/download/pdf/left main stenosispercutaneous coronary interven |
| spellingShingle | Ivayla Zheleva-Kyuchukova Valeri Gelev Is left main percutaneous coronary intervention justified in the presence of concomitant complex coronary artery disease – immediate and remote results – single Bulgarian center experience Българска кардиология left main stenosis percutaneous coronary interven |
| title | Is left main percutaneous coronary intervention justified in the presence of concomitant complex coronary artery disease – immediate and remote results – single Bulgarian center experience |
| title_full | Is left main percutaneous coronary intervention justified in the presence of concomitant complex coronary artery disease – immediate and remote results – single Bulgarian center experience |
| title_fullStr | Is left main percutaneous coronary intervention justified in the presence of concomitant complex coronary artery disease – immediate and remote results – single Bulgarian center experience |
| title_full_unstemmed | Is left main percutaneous coronary intervention justified in the presence of concomitant complex coronary artery disease – immediate and remote results – single Bulgarian center experience |
| title_short | Is left main percutaneous coronary intervention justified in the presence of concomitant complex coronary artery disease – immediate and remote results – single Bulgarian center experience |
| title_sort | is left main percutaneous coronary intervention justified in the presence of concomitant complex coronary artery disease immediate and remote results single bulgarian center experience |
| topic | left main stenosis percutaneous coronary interven |
| url | https://journal.bgcardio.org/article/54126/download/pdf/ |
| work_keys_str_mv | AT ivaylazhelevakyuchukova isleftmainpercutaneouscoronaryinterventionjustifiedinthepresenceofconcomitantcomplexcoronaryarterydiseaseimmediateandremoteresultssinglebulgariancenterexperience AT valerigelev isleftmainpercutaneouscoronaryinterventionjustifiedinthepresenceofconcomitantcomplexcoronaryarterydiseaseimmediateandremoteresultssinglebulgariancenterexperience |