A novel non-linear approach for establishing a QSAR model of a class of 2-Phenyl-3-(pyridin-2-yl) thiazolidin-4-one derivatives

A novel non-linear approach for establishing a QSAR model of a class of 2-Phenyl-3-(pyridin-2-yl) thiazolidin-4-one derivatives

In this investigation, we aimed to address the pressing challenge of treating osteosarcoma, a prevalent and difficult-to-treat form of cancer. To achieve this, we developed a quantitative structure-activity relationship (QSAR) model focused on a specific class of compounds called 2-Phenyl-3-(pyridin...

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Bibliographic Details
Main Authors: Leilei Wu, Yonglin Chen, Kangying Duan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Pharmacology
Subjects:
osteosarcoma
QSAR
gene expression programming
model
non-linear
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1263933/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1263933/full

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