Bridging the gap between microbial limits and extremes in space: space microbial biotechnology in the next 15 years
Summary The establishment of a permanent human settlement in space is one of humanity’s ambitions. To achieve this, microorganisms will be used to carry out many functions such as recycling, food and pharmaceutical production, mining and other processes. However, the physical and chemical extremes i...
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Microbial Biotechnology |
| Online Access: | https://doi.org/10.1111/1751-7915.13927 |
| _version_ | 1797995957145567232 |
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| author | Charles S. Cockell |
| author_facet | Charles S. Cockell |
| author_sort | Charles S. Cockell |
| collection | DOAJ |
| description | Summary The establishment of a permanent human settlement in space is one of humanity’s ambitions. To achieve this, microorganisms will be used to carry out many functions such as recycling, food and pharmaceutical production, mining and other processes. However, the physical and chemical extremes in all locations beyond Earth exceed known growth limits of microbial life. Making microbes more tolerant of a greater range of extraterrestrial extremes will not produce organisms that can grow in unmodified extraterrestrial environments since in many of them not even liquid water can exist. However, by narrowing the gap, the engineering demands on bioindustrial processes can be reduced and greater robustness can be incorporated into the biological component. I identify and describe these required microbial biotechnological modifications and speculate on long‐term possibilities such as microbial biotechnology on Saturn’s moon Titan to support a human presence in the outer Solar System and bioprocessing of asteroids. A challenge for space microbial biotechnology in the coming decades is to narrow the microbial gap by systemically identifying the genes required to do this and incorporating them into microbial systems that can be used to carry out bioindustrial processes of interest. |
| first_indexed | 2024-04-11T10:08:43Z |
| format | Article |
| id | doaj.art-c573a047764c4fa594b652dcb09822c9 |
| institution | Directory Open Access Journal |
| issn | 1751-7915 |
| language | English |
| last_indexed | 2024-04-11T10:08:43Z |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Microbial Biotechnology |
| spelling | doaj.art-c573a047764c4fa594b652dcb09822c92022-12-22T04:30:09ZengWileyMicrobial Biotechnology1751-79152022-01-01151294110.1111/1751-7915.13927Bridging the gap between microbial limits and extremes in space: space microbial biotechnology in the next 15 yearsCharles S. Cockell0UK Centre for Astrobiology School of Physics and Astronomy University of Edinburgh Edinburgh UKSummary The establishment of a permanent human settlement in space is one of humanity’s ambitions. To achieve this, microorganisms will be used to carry out many functions such as recycling, food and pharmaceutical production, mining and other processes. However, the physical and chemical extremes in all locations beyond Earth exceed known growth limits of microbial life. Making microbes more tolerant of a greater range of extraterrestrial extremes will not produce organisms that can grow in unmodified extraterrestrial environments since in many of them not even liquid water can exist. However, by narrowing the gap, the engineering demands on bioindustrial processes can be reduced and greater robustness can be incorporated into the biological component. I identify and describe these required microbial biotechnological modifications and speculate on long‐term possibilities such as microbial biotechnology on Saturn’s moon Titan to support a human presence in the outer Solar System and bioprocessing of asteroids. A challenge for space microbial biotechnology in the coming decades is to narrow the microbial gap by systemically identifying the genes required to do this and incorporating them into microbial systems that can be used to carry out bioindustrial processes of interest.https://doi.org/10.1111/1751-7915.13927 |
| spellingShingle | Charles S. Cockell Bridging the gap between microbial limits and extremes in space: space microbial biotechnology in the next 15 years Microbial Biotechnology |
| title | Bridging the gap between microbial limits and extremes in space: space microbial biotechnology in the next 15 years |
| title_full | Bridging the gap between microbial limits and extremes in space: space microbial biotechnology in the next 15 years |
| title_fullStr | Bridging the gap between microbial limits and extremes in space: space microbial biotechnology in the next 15 years |
| title_full_unstemmed | Bridging the gap between microbial limits and extremes in space: space microbial biotechnology in the next 15 years |
| title_short | Bridging the gap between microbial limits and extremes in space: space microbial biotechnology in the next 15 years |
| title_sort | bridging the gap between microbial limits and extremes in space space microbial biotechnology in the next 15 years |
| url | https://doi.org/10.1111/1751-7915.13927 |
| work_keys_str_mv | AT charlesscockell bridgingthegapbetweenmicrobiallimitsandextremesinspacespacemicrobialbiotechnologyinthenext15years |