Multiple synchronous primary lung adenocarcinomas with distinct epidermal growth factor receptor mutations: A case report
An 83-year-old woman presents with two synchronous primary lung adenocarcinomas each harboring unique EGFR mutations, one classical and the other rare. She was treated with adjuvant Osimertinib following surgical lobectomy and remains well 44 months from the time of her diagnosis. Her case demonstra...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-09-01
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| Series: | Current Problems in Cancer: Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666621922000357 |
| Summary: | An 83-year-old woman presents with two synchronous primary lung adenocarcinomas each harboring unique EGFR mutations, one classical and the other rare. She was treated with adjuvant Osimertinib following surgical lobectomy and remains well 44 months from the time of her diagnosis. Her case demonstrates the potential value in using EGFR third generation TKI monotherapy in patients with early-stage disease, harboring rare mutations and in patients with multiple primary cancers harboring targetable mutations. Further research into the use of targeted therapy in these areas is needed. |
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| ISSN: | 2666-6219 |