Multilevel Deep Feature Generation Framework for Automated Detection of Retinal Abnormalities Using OCT Images

Optical coherence tomography (OCT) images coupled with many learning techniques have been developed to diagnose retinal disorders. This work aims to develop a novel framework for extracting deep features from 18 pre-trained convolutional neural networks (CNN) and to attain high performance using OCT...

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Main Authors: Prabal Datta Barua, Wai Yee Chan, Sengul Dogan, Mehmet Baygin, Turker Tuncer, Edward J. Ciaccio, Nazrul Islam, Kang Hao Cheong, Zakia Sultana Shahid, U. Rajendra Acharya
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Entropy
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Online Access:https://www.mdpi.com/1099-4300/23/12/1651
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author Prabal Datta Barua
Wai Yee Chan
Sengul Dogan
Mehmet Baygin
Turker Tuncer
Edward J. Ciaccio
Nazrul Islam
Kang Hao Cheong
Zakia Sultana Shahid
U. Rajendra Acharya
author_facet Prabal Datta Barua
Wai Yee Chan
Sengul Dogan
Mehmet Baygin
Turker Tuncer
Edward J. Ciaccio
Nazrul Islam
Kang Hao Cheong
Zakia Sultana Shahid
U. Rajendra Acharya
author_sort Prabal Datta Barua
collection DOAJ
description Optical coherence tomography (OCT) images coupled with many learning techniques have been developed to diagnose retinal disorders. This work aims to develop a novel framework for extracting deep features from 18 pre-trained convolutional neural networks (CNN) and to attain high performance using OCT images. In this work, we have developed a new framework for automated detection of retinal disorders using transfer learning. This model consists of three phases: deep fused and multilevel feature extraction, using 18 pre-trained networks and tent maximal pooling, feature selection with ReliefF, and classification using the optimized classifier. The novelty of this proposed framework is the feature generation using widely used CNNs and to select the most suitable features for classification. The extracted features using our proposed intelligent feature extractor are fed to iterative ReliefF (IRF) to automatically select the best feature vector. The quadratic support vector machine (QSVM) is utilized as a classifier in this work. We have developed our model using two public OCT image datasets, and they are named database 1 (DB1) and database 2 (DB2). The proposed framework can attain 97.40% and 100% classification accuracies using the two OCT datasets, DB1 and DB2, respectively. These results illustrate the success of our model.
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spelling doaj.art-c577473323ae4fa5af86fc6fcb126b0c2023-11-23T08:11:09ZengMDPI AGEntropy1099-43002021-12-012312165110.3390/e23121651Multilevel Deep Feature Generation Framework for Automated Detection of Retinal Abnormalities Using OCT ImagesPrabal Datta Barua0Wai Yee Chan1Sengul Dogan2Mehmet Baygin3Turker Tuncer4Edward J. Ciaccio5Nazrul Islam6Kang Hao Cheong7Zakia Sultana Shahid8U. Rajendra Acharya9School of Management & Enterprise, University of Southern Queensland, Toowoomba, QLD 4350, AustraliaUniversity Malaya Research Imaging Centre, Department of Biomedical Imaging, Faculty of Medicine, University of Malaya, Kuala Lumpur 59100, MalaysiaDepartment of Digital Forensics Engineering, College of Technology, Firat University, Elazig 23002, TurkeyDepartment of Computer Engineering, College of Engineering, Ardahan University, Ardahan 75000, TurkeyDepartment of Digital Forensics Engineering, College of Technology, Firat University, Elazig 23002, TurkeyDepartment of Medicine, Columbia University Irving Medical Center, New York, NY 10032-3784, USAGlaucoma Faculty, Bangladesh Eye Hospital & Institute, Dhaka 1206, BangladeshScience, Mathematics and Technology Cluster, Singapore University of Technology and Design, Singapore 487372, SingaporeDepartment of Ophthalmology, Anwer Khan Modern Medical College, Dhaka 1205, BangladeshDepartment of Electronics and Computer Engineering, Ngee Ann Polytechnic, Singapore 599489, SingaporeOptical coherence tomography (OCT) images coupled with many learning techniques have been developed to diagnose retinal disorders. This work aims to develop a novel framework for extracting deep features from 18 pre-trained convolutional neural networks (CNN) and to attain high performance using OCT images. In this work, we have developed a new framework for automated detection of retinal disorders using transfer learning. This model consists of three phases: deep fused and multilevel feature extraction, using 18 pre-trained networks and tent maximal pooling, feature selection with ReliefF, and classification using the optimized classifier. The novelty of this proposed framework is the feature generation using widely used CNNs and to select the most suitable features for classification. The extracted features using our proposed intelligent feature extractor are fed to iterative ReliefF (IRF) to automatically select the best feature vector. The quadratic support vector machine (QSVM) is utilized as a classifier in this work. We have developed our model using two public OCT image datasets, and they are named database 1 (DB1) and database 2 (DB2). The proposed framework can attain 97.40% and 100% classification accuracies using the two OCT datasets, DB1 and DB2, respectively. These results illustrate the success of our model.https://www.mdpi.com/1099-4300/23/12/1651OCT image classificationdiabetic macular edema (DME)hybrid deep feature generationiterative feature selectiondigital image processing
spellingShingle Prabal Datta Barua
Wai Yee Chan
Sengul Dogan
Mehmet Baygin
Turker Tuncer
Edward J. Ciaccio
Nazrul Islam
Kang Hao Cheong
Zakia Sultana Shahid
U. Rajendra Acharya
Multilevel Deep Feature Generation Framework for Automated Detection of Retinal Abnormalities Using OCT Images
Entropy
OCT image classification
diabetic macular edema (DME)
hybrid deep feature generation
iterative feature selection
digital image processing
title Multilevel Deep Feature Generation Framework for Automated Detection of Retinal Abnormalities Using OCT Images
title_full Multilevel Deep Feature Generation Framework for Automated Detection of Retinal Abnormalities Using OCT Images
title_fullStr Multilevel Deep Feature Generation Framework for Automated Detection of Retinal Abnormalities Using OCT Images
title_full_unstemmed Multilevel Deep Feature Generation Framework for Automated Detection of Retinal Abnormalities Using OCT Images
title_short Multilevel Deep Feature Generation Framework for Automated Detection of Retinal Abnormalities Using OCT Images
title_sort multilevel deep feature generation framework for automated detection of retinal abnormalities using oct images
topic OCT image classification
diabetic macular edema (DME)
hybrid deep feature generation
iterative feature selection
digital image processing
url https://www.mdpi.com/1099-4300/23/12/1651
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