Non‐medical oocyte cryopreservation at a single center in Japan: 8 years of experience
Abstract Purpose Increasing numbers of women are opting to undergo non‐medical oocyte cryopreservation (NMOC). In this report, we present experience at our clinic and discuss NMOC in Japan. Methods We followed the progress of 403 women who underwent NMOC at our clinic between 2014 and 2021, totaling...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-01-01
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| Series: | Reproductive Medicine and Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/rmb2.12549 |
| _version_ | 1797376238905458688 |
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| author | Koki Yoshinaga Tomoko Hashimoto Yuriko Fukuoka Noriyuki Okuyama Koichi Kyono |
| author_facet | Koki Yoshinaga Tomoko Hashimoto Yuriko Fukuoka Noriyuki Okuyama Koichi Kyono |
| author_sort | Koki Yoshinaga |
| collection | DOAJ |
| description | Abstract Purpose Increasing numbers of women are opting to undergo non‐medical oocyte cryopreservation (NMOC). In this report, we present experience at our clinic and discuss NMOC in Japan. Methods We followed the progress of 403 women who underwent NMOC at our clinic between 2014 and 2021, totaling 592 reproductive cycles. Results In total, 61 women underwent oocyte warming and fertility treatment. Of these, 13 women gave birth to 14 children. The median age at first oocyte cryopreservation was 38.3 years, and the oldest pregnant woman was 42 years. Most clients (60%) were in their late 30s. The median time between first oocyte cryopreservation and warming was 3.0 years. One woman was able to achieve a live birth with four vitrified oocytes. Conclusions This is the first report in Japan documenting pregnancies and childbirths resulting from NMOC. Ideally, women hope to achieve natural pregnancy between 20 and 32 years of age. NMOC is an option for individuals who are unable to pursue pregnancy during optimal reproductive years and wish to preserve their fertility for future attempts. NMOC is recommended in cases with few indications, and it is necessary to continue accumulating data on its long‐term safety and effectiveness. |
| first_indexed | 2024-03-08T19:35:45Z |
| format | Article |
| id | doaj.art-c57b228f33c845a3bdb72927417ab3f9 |
| institution | Directory Open Access Journal |
| issn | 1445-5781 1447-0578 |
| language | English |
| last_indexed | 2024-03-08T19:35:45Z |
| publishDate | 2023-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Reproductive Medicine and Biology |
| spelling | doaj.art-c57b228f33c845a3bdb72927417ab3f92023-12-26T04:30:44ZengWileyReproductive Medicine and Biology1445-57811447-05782023-01-01221n/an/a10.1002/rmb2.12549Non‐medical oocyte cryopreservation at a single center in Japan: 8 years of experienceKoki Yoshinaga0Tomoko Hashimoto1Yuriko Fukuoka2Noriyuki Okuyama3Koichi Kyono4Kyono ART Clinic Takanawa Tokyo JapanKyono ART Clinic Takanawa Tokyo JapanKyono ART Clinic Takanawa Tokyo JapanKyono ART Clinic Takanawa Tokyo JapanKyono ART Clinic Takanawa Tokyo JapanAbstract Purpose Increasing numbers of women are opting to undergo non‐medical oocyte cryopreservation (NMOC). In this report, we present experience at our clinic and discuss NMOC in Japan. Methods We followed the progress of 403 women who underwent NMOC at our clinic between 2014 and 2021, totaling 592 reproductive cycles. Results In total, 61 women underwent oocyte warming and fertility treatment. Of these, 13 women gave birth to 14 children. The median age at first oocyte cryopreservation was 38.3 years, and the oldest pregnant woman was 42 years. Most clients (60%) were in their late 30s. The median time between first oocyte cryopreservation and warming was 3.0 years. One woman was able to achieve a live birth with four vitrified oocytes. Conclusions This is the first report in Japan documenting pregnancies and childbirths resulting from NMOC. Ideally, women hope to achieve natural pregnancy between 20 and 32 years of age. NMOC is an option for individuals who are unable to pursue pregnancy during optimal reproductive years and wish to preserve their fertility for future attempts. NMOC is recommended in cases with few indications, and it is necessary to continue accumulating data on its long‐term safety and effectiveness.https://doi.org/10.1002/rmb2.12549clinical outcomeegg freezingfertility preservationnon‐medical oocyte cryopreservationvitrification |
| spellingShingle | Koki Yoshinaga Tomoko Hashimoto Yuriko Fukuoka Noriyuki Okuyama Koichi Kyono Non‐medical oocyte cryopreservation at a single center in Japan: 8 years of experience Reproductive Medicine and Biology clinical outcome egg freezing fertility preservation non‐medical oocyte cryopreservation vitrification |
| title | Non‐medical oocyte cryopreservation at a single center in Japan: 8 years of experience |
| title_full | Non‐medical oocyte cryopreservation at a single center in Japan: 8 years of experience |
| title_fullStr | Non‐medical oocyte cryopreservation at a single center in Japan: 8 years of experience |
| title_full_unstemmed | Non‐medical oocyte cryopreservation at a single center in Japan: 8 years of experience |
| title_short | Non‐medical oocyte cryopreservation at a single center in Japan: 8 years of experience |
| title_sort | non medical oocyte cryopreservation at a single center in japan 8 years of experience |
| topic | clinical outcome egg freezing fertility preservation non‐medical oocyte cryopreservation vitrification |
| url | https://doi.org/10.1002/rmb2.12549 |
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