Optimized haemostasis in nephron-sparing surgery using small-intestine submucosa
<p>Abstract</p> <p>Background</p> <p>The indications for nephron-sparing surgery are expanding constantly. One major contributing fact for this development is the improvement of haemostatic techniques following excision of the tumor. Nevertheless, postoperative bleeding...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2008-04-01
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| Series: | BMC Urology |
| Online Access: | http://www.biomedcentral.com/1471-2490/8/8 |
| _version_ | 1811320471519494144 |
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| author | Hautmann Richard E Meilinger Michael de Petriconi Robert Simon Jörg Bartsch Georg |
| author_facet | Hautmann Richard E Meilinger Michael de Petriconi Robert Simon Jörg Bartsch Georg |
| author_sort | Hautmann Richard E |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>The indications for nephron-sparing surgery are expanding constantly. One major contributing fact for this development is the improvement of haemostatic techniques following excision of the tumor. Nevertheless, postoperative bleeding complications still occur. To prevent this, we prospectively studied the effect of application of small-intestine submucosa (SIS) over the renal defect.</p> <p>Methods</p> <p>We performed 55 nephron-sparing surgeries applying SIS between 08/03 and 10/06 in 53 pts. (mean age: 59 yrs., range 29 – 79 yrs.). After resection of the renal tumor and application of a haemostyptic agent, we used SIS to secure and apply compression on the defect.</p> <p>Results</p> <p>The final pathology revealed clear-cell and papillary carcinoma, papillary adenoma, oncocytoma, and angiomyolipoma in 39 (70.9%), 6 (10.9), 1 (1.8%), 2 (3.6%) and 7 (12.7%) patients, respectively. The 45 malignant lesions (81.8%) were classified as pT1a and pT1b in 35 (77.8%) and 10 (22.2%) patients, respectively. The median tumor size was 4.5 cm (range: 1.3 – 13 cm). The median operating time was 186 min (range: 90 – 260 min). 18 (32.7%) procedures were performed without ischemia. 23 (41.8%) and 14 (25.5%) cases were operated in in-situ cold and warm ischemia, respectively. The median intraoperative blood loss was 730 cc (range: 100 – 2500 cc). No open operative revision was indicated due to postoperative bleeding complications. Furthermore, there was no necessity to substitute persistent blood loss from the drains postoperatively. No urinoma occurred.</p> <p>Conclusion</p> <p>SIS is a highly effective and easy-to-use instrument for preventing postoperative bleeding and urinary fistula complications in nephron-sparing surgery.</p> |
| first_indexed | 2024-04-13T12:59:53Z |
| format | Article |
| id | doaj.art-c57dd567b6554945a085412f0d88a1dc |
| institution | Directory Open Access Journal |
| issn | 1471-2490 |
| language | English |
| last_indexed | 2024-04-13T12:59:53Z |
| publishDate | 2008-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Urology |
| spelling | doaj.art-c57dd567b6554945a085412f0d88a1dc2022-12-22T02:45:57ZengBMCBMC Urology1471-24902008-04-0181810.1186/1471-2490-8-8Optimized haemostasis in nephron-sparing surgery using small-intestine submucosaHautmann Richard EMeilinger Michaelde Petriconi RobertSimon JörgBartsch Georg<p>Abstract</p> <p>Background</p> <p>The indications for nephron-sparing surgery are expanding constantly. One major contributing fact for this development is the improvement of haemostatic techniques following excision of the tumor. Nevertheless, postoperative bleeding complications still occur. To prevent this, we prospectively studied the effect of application of small-intestine submucosa (SIS) over the renal defect.</p> <p>Methods</p> <p>We performed 55 nephron-sparing surgeries applying SIS between 08/03 and 10/06 in 53 pts. (mean age: 59 yrs., range 29 – 79 yrs.). After resection of the renal tumor and application of a haemostyptic agent, we used SIS to secure and apply compression on the defect.</p> <p>Results</p> <p>The final pathology revealed clear-cell and papillary carcinoma, papillary adenoma, oncocytoma, and angiomyolipoma in 39 (70.9%), 6 (10.9), 1 (1.8%), 2 (3.6%) and 7 (12.7%) patients, respectively. The 45 malignant lesions (81.8%) were classified as pT1a and pT1b in 35 (77.8%) and 10 (22.2%) patients, respectively. The median tumor size was 4.5 cm (range: 1.3 – 13 cm). The median operating time was 186 min (range: 90 – 260 min). 18 (32.7%) procedures were performed without ischemia. 23 (41.8%) and 14 (25.5%) cases were operated in in-situ cold and warm ischemia, respectively. The median intraoperative blood loss was 730 cc (range: 100 – 2500 cc). No open operative revision was indicated due to postoperative bleeding complications. Furthermore, there was no necessity to substitute persistent blood loss from the drains postoperatively. No urinoma occurred.</p> <p>Conclusion</p> <p>SIS is a highly effective and easy-to-use instrument for preventing postoperative bleeding and urinary fistula complications in nephron-sparing surgery.</p>http://www.biomedcentral.com/1471-2490/8/8 |
| spellingShingle | Hautmann Richard E Meilinger Michael de Petriconi Robert Simon Jörg Bartsch Georg Optimized haemostasis in nephron-sparing surgery using small-intestine submucosa BMC Urology |
| title | Optimized haemostasis in nephron-sparing surgery using small-intestine submucosa |
| title_full | Optimized haemostasis in nephron-sparing surgery using small-intestine submucosa |
| title_fullStr | Optimized haemostasis in nephron-sparing surgery using small-intestine submucosa |
| title_full_unstemmed | Optimized haemostasis in nephron-sparing surgery using small-intestine submucosa |
| title_short | Optimized haemostasis in nephron-sparing surgery using small-intestine submucosa |
| title_sort | optimized haemostasis in nephron sparing surgery using small intestine submucosa |
| url | http://www.biomedcentral.com/1471-2490/8/8 |
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