Long-Term Effect of Post-traumatic Stress in Adolescence on Dendrite Development and H3K9me2/BDNF Expression in Male Rat Hippocampus and Prefrontal Cortex

Long-Term Effect of Post-traumatic Stress in Adolescence on Dendrite Development and H3K9me2/BDNF Expression in Male Rat Hippocampus and Prefrontal Cortex

Exposure to a harsh environment in early life increases in the risk of post-traumatic stress disorder (PTSD) of an individual. Brain derived neurotrophic factor (BDNF) plays an important role in neurodevelopment in developmental stages. Both chronic and traumatic stresses induce a decrease in the le...

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Bibliographic Details
Main Authors: Mingyue Zhao, Wei Wang, Zhijun Jiang, Zemeng Zhu, Dexiang Liu, Fang Pan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
PTSD
BDNF
H3K9me2
neurodevelopment
methylation
epigenetic
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00682/full

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