Diabetes mellitus drug discovery: insights into targeting feline and human amylin with small molecules

Diabetes mellitus drug discovery: insights into targeting feline and human amylin with small molecules

AbstractBackground Type 2 diabetes (T2D) is a health concern for both humans and cats, with cases rising over the past decade. Around 70% of patients from either species exhibit pancreatic aggregates of islet amyloid polypeptide (IAPP), a protein that proves toxic upon misfolding. These misfolded pr...

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Bibliographic Details
Main Authors: Kendall B. E. Moore, Natalie G. Horgan, Brooke Lenters, Jessica S. Fortin
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Veterinary Quarterly
Subjects:
Amylin
cat
drug discovery
islet amyloid polypeptide
pancreatic amyloidosis
type 2 diabetes
Online Access:https://www.tandfonline.com/doi/10.1080/01652176.2023.2260442

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