miR-18a impairs DNA damage response through downregulation of ataxia telangiectasia mutated (ATM) kinase.

miR-18a impairs DNA damage response through downregulation of ataxia telangiectasia mutated (ATM) kinase.

The DNA damage response (DDR) encompasses multi-step processes by which cells evolve to sense DNA damage, transduce the signal and initiate the repair of damaged DNA. Ataxia Telangiectasia Mutated (ATM) Kinase, which functions as the primary sensor and transducer of DNA damage signal, has been demon...

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Bibliographic Details
Main Authors: Libing Song, Chuyong Lin, Zhiqiang Wu, Hui Gong, Yong Zeng, Jueheng Wu, Mengfeng Li, Jun Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3181320?pdf=render

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