Effects of age and gender on body composition indices as predictors of mortality in middle-aged and old people
Abstract To determine whether body composition indices interact with age and gender as a predictor of all-cause mortality, 1200 participants at least 40 years of age were recruited in 2009 and 2010. A multi-frequency bioelectrical impedance analysis device was used to measure each participant’s body...
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| Format: | Article |
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Nature Portfolio
2022-05-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-022-12048-0 |
| _version_ | 1811253206787817472 |
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| author | Chin-Sung Chang I-Ting Liu Fu-Wen Liang Chia-Chun Li Zih-Jie Sun Yin-Fan Chang Ting-Hsing Chao Chih-Hsing Wu |
| author_facet | Chin-Sung Chang I-Ting Liu Fu-Wen Liang Chia-Chun Li Zih-Jie Sun Yin-Fan Chang Ting-Hsing Chao Chih-Hsing Wu |
| author_sort | Chin-Sung Chang |
| collection | DOAJ |
| description | Abstract To determine whether body composition indices interact with age and gender as a predictor of all-cause mortality, 1200 participants at least 40 years of age were recruited in 2009 and 2010. A multi-frequency bioelectrical impedance analysis device was used to measure each participant’s body composition indices, including the fat mass index (FMI), fat free mass index (FFMI), skeletal muscle mass index (SMMI), and visceral fat area index (VFAI). A baseline questionnaire was used to collect demographic information about lifestyle habits, socioeconomic status, and medical conditions. All claimed records of death from 2009 to 2018 in the National Health Insurance Research Databank were identified. The all-cause mortality rate was 8.67% after a mean follow-up period of 5.86 ± 2.39 person-years. The Cox proportional hazard model analysis showed significantly negative associations between FFMI or SMMI with all-cause mortality in the total group and those aged $$\geq$$ ≥ 65 y/o. The FFMI and SMMI were negative predictors of mortality in both genders. The FMI and VFAI were positive predictors of mortality exclusively in females. In conclusion, the SMMI is a better predictor of mortality than the BMI, FMI, and FFMI, especially in older adults. A higher fat mass or visceral fat distribution may predict higher mortality in females. |
| first_indexed | 2024-04-12T16:47:25Z |
| format | Article |
| id | doaj.art-c58753ac78764e7c9cecaf6f729b7d3a |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-12T16:47:25Z |
| publishDate | 2022-05-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-c58753ac78764e7c9cecaf6f729b7d3a2022-12-22T03:24:32ZengNature PortfolioScientific Reports2045-23222022-05-011211910.1038/s41598-022-12048-0Effects of age and gender on body composition indices as predictors of mortality in middle-aged and old peopleChin-Sung Chang0I-Ting Liu1Fu-Wen Liang2Chia-Chun Li3Zih-Jie Sun4Yin-Fan Chang5Ting-Hsing Chao6Chih-Hsing Wu7Department of Family Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung UniversityDepartment of Family Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung UniversityDepartment of Public Health, Kaohsiung Medical UniversityDepartment of Family Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung UniversityDepartment of Family Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung UniversityDepartment of Family Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung UniversityDepartment of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung UniversityDepartment of Family Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung UniversityAbstract To determine whether body composition indices interact with age and gender as a predictor of all-cause mortality, 1200 participants at least 40 years of age were recruited in 2009 and 2010. A multi-frequency bioelectrical impedance analysis device was used to measure each participant’s body composition indices, including the fat mass index (FMI), fat free mass index (FFMI), skeletal muscle mass index (SMMI), and visceral fat area index (VFAI). A baseline questionnaire was used to collect demographic information about lifestyle habits, socioeconomic status, and medical conditions. All claimed records of death from 2009 to 2018 in the National Health Insurance Research Databank were identified. The all-cause mortality rate was 8.67% after a mean follow-up period of 5.86 ± 2.39 person-years. The Cox proportional hazard model analysis showed significantly negative associations between FFMI or SMMI with all-cause mortality in the total group and those aged $$\geq$$ ≥ 65 y/o. The FFMI and SMMI were negative predictors of mortality in both genders. The FMI and VFAI were positive predictors of mortality exclusively in females. In conclusion, the SMMI is a better predictor of mortality than the BMI, FMI, and FFMI, especially in older adults. A higher fat mass or visceral fat distribution may predict higher mortality in females.https://doi.org/10.1038/s41598-022-12048-0 |
| spellingShingle | Chin-Sung Chang I-Ting Liu Fu-Wen Liang Chia-Chun Li Zih-Jie Sun Yin-Fan Chang Ting-Hsing Chao Chih-Hsing Wu Effects of age and gender on body composition indices as predictors of mortality in middle-aged and old people Scientific Reports |
| title | Effects of age and gender on body composition indices as predictors of mortality in middle-aged and old people |
| title_full | Effects of age and gender on body composition indices as predictors of mortality in middle-aged and old people |
| title_fullStr | Effects of age and gender on body composition indices as predictors of mortality in middle-aged and old people |
| title_full_unstemmed | Effects of age and gender on body composition indices as predictors of mortality in middle-aged and old people |
| title_short | Effects of age and gender on body composition indices as predictors of mortality in middle-aged and old people |
| title_sort | effects of age and gender on body composition indices as predictors of mortality in middle aged and old people |
| url | https://doi.org/10.1038/s41598-022-12048-0 |
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