Hypoxia regulates human lung fibroblast proliferation via p53-dependent and -independent pathways

Hypoxia regulates human lung fibroblast proliferation via p53-dependent and -independent pathways

<p>Abstract</p> <p>Background</p> <p>Hypoxia induces the proliferation of lung fibroblasts in vivo and in vitro. However, the subcellular interactions between hypoxia and expression of tumor suppressor p53 and cyclin-dependent kinase inhibitors p21 and p27 remain unclea...

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Bibliographic Details
Main Authors: Ameshima Shingo, Kadowaki Maiko, Umeda Yukihiro, Voelkel Norbert F, Bogaard Herman J, Mizuno Shiro, Miyamori Isamu, Ishizaki Takeshi
Format: Article
Language:English
Published: BMC 2009-03-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/10/1/17

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