Preparation of Thermo-Sensitive Molecular Imprinted SERS Substrate with Robust Recyclability for Detection of Ofloxacin
To this day, the preparation of surface-enhanced Raman spectroscopy (SERS) substrates with high sensitivity, selectivity, and stability has been the bottleneck to realizing SERS-based quantitative analysis in practical applications. In this paper, a thermo-sensitive imprinting SERS substrate materia...
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| Format: | Article |
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MDPI AG
2022-10-01
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| Series: | Chemosensors |
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| Online Access: | https://www.mdpi.com/2227-9040/10/11/437 |
| _version_ | 1797468739106504704 |
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| author | Caiyun Jiang Ting Wu Xin He Yuping Wang Hong-zhen Lian |
| author_facet | Caiyun Jiang Ting Wu Xin He Yuping Wang Hong-zhen Lian |
| author_sort | Caiyun Jiang |
| collection | DOAJ |
| description | To this day, the preparation of surface-enhanced Raman spectroscopy (SERS) substrates with high sensitivity, selectivity, and stability has been the bottleneck to realizing SERS-based quantitative analysis in practical applications. In this paper, a thermo-sensitive imprinting SERS substrate material (TM@TiO<sub>2</sub>@Ag) is developed with a uniform structure and morphology, a controllable “hot spot” and photocatalytic regeneration. The as-prepared TM@TiO<sub>2</sub>@Ag nanocomposite is characterized by scanning electron microscopy, transmission electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction, dynamic light scattering, ultraviolet–visible (UV-Vis) spectroscopy, etc. After the effects of its thermo-sensitive property on localized surface plasmon resonance (LSPR) and SERS signals are investigated, this nanomaterial is used as the Raman-enhanced substrate for rapid and trace detection of ofloxacin (OFL) in water. It is found that, with the aid of unique structure and composition, temperature sensitivity, and molecule imprinting, the SERS sensor possesses considerably strong anti-interference ability not only to structure-unlike but also to structure-like co-existing substances, extremely low detectable concentration of 1.1 × 10<sup>−</sup><sup>11</sup> M for OFL at 1397 cm<sup>−1</sup>, as well as excellent reusability due to its photocatalytic degradation to target analytes. |
| first_indexed | 2024-03-09T19:11:42Z |
| format | Article |
| id | doaj.art-c58dbaaeb0b545d0bb18dc8fe0865f53 |
| institution | Directory Open Access Journal |
| issn | 2227-9040 |
| language | English |
| last_indexed | 2024-03-09T19:11:42Z |
| publishDate | 2022-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Chemosensors |
| spelling | doaj.art-c58dbaaeb0b545d0bb18dc8fe0865f532023-11-24T04:10:12ZengMDPI AGChemosensors2227-90402022-10-01101143710.3390/chemosensors10110437Preparation of Thermo-Sensitive Molecular Imprinted SERS Substrate with Robust Recyclability for Detection of OfloxacinCaiyun Jiang0Ting Wu1Xin He2Yuping Wang3Hong-zhen Lian4Department of Engineering and Technology, Jiangsu Engineering and Research Center of Food Safety, Jiangsu Vocational Institute of Commerce, Nanjing 210007, ChinaCollege of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210023, ChinaCollege of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210023, ChinaCollege of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210023, ChinaState Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry & Chemical Engineering and Center of Materials Analysis, Nanjing University, Nanjing 210023, ChinaTo this day, the preparation of surface-enhanced Raman spectroscopy (SERS) substrates with high sensitivity, selectivity, and stability has been the bottleneck to realizing SERS-based quantitative analysis in practical applications. In this paper, a thermo-sensitive imprinting SERS substrate material (TM@TiO<sub>2</sub>@Ag) is developed with a uniform structure and morphology, a controllable “hot spot” and photocatalytic regeneration. The as-prepared TM@TiO<sub>2</sub>@Ag nanocomposite is characterized by scanning electron microscopy, transmission electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction, dynamic light scattering, ultraviolet–visible (UV-Vis) spectroscopy, etc. After the effects of its thermo-sensitive property on localized surface plasmon resonance (LSPR) and SERS signals are investigated, this nanomaterial is used as the Raman-enhanced substrate for rapid and trace detection of ofloxacin (OFL) in water. It is found that, with the aid of unique structure and composition, temperature sensitivity, and molecule imprinting, the SERS sensor possesses considerably strong anti-interference ability not only to structure-unlike but also to structure-like co-existing substances, extremely low detectable concentration of 1.1 × 10<sup>−</sup><sup>11</sup> M for OFL at 1397 cm<sup>−1</sup>, as well as excellent reusability due to its photocatalytic degradation to target analytes.https://www.mdpi.com/2227-9040/10/11/437SERSmolecule imprintingthermo-sensitiverecyclabilityofloxacin (OFL) |
| spellingShingle | Caiyun Jiang Ting Wu Xin He Yuping Wang Hong-zhen Lian Preparation of Thermo-Sensitive Molecular Imprinted SERS Substrate with Robust Recyclability for Detection of Ofloxacin Chemosensors SERS molecule imprinting thermo-sensitive recyclability ofloxacin (OFL) |
| title | Preparation of Thermo-Sensitive Molecular Imprinted SERS Substrate with Robust Recyclability for Detection of Ofloxacin |
| title_full | Preparation of Thermo-Sensitive Molecular Imprinted SERS Substrate with Robust Recyclability for Detection of Ofloxacin |
| title_fullStr | Preparation of Thermo-Sensitive Molecular Imprinted SERS Substrate with Robust Recyclability for Detection of Ofloxacin |
| title_full_unstemmed | Preparation of Thermo-Sensitive Molecular Imprinted SERS Substrate with Robust Recyclability for Detection of Ofloxacin |
| title_short | Preparation of Thermo-Sensitive Molecular Imprinted SERS Substrate with Robust Recyclability for Detection of Ofloxacin |
| title_sort | preparation of thermo sensitive molecular imprinted sers substrate with robust recyclability for detection of ofloxacin |
| topic | SERS molecule imprinting thermo-sensitive recyclability ofloxacin (OFL) |
| url | https://www.mdpi.com/2227-9040/10/11/437 |
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