Inequality in the Frequency of the Open States Occurrence Depends on Single <sup>2</sup>H/<sup>1</sup>H Replacement in DNA

Inequality in the Frequency of the Open States Occurrence Depends on Single <sup>2</sup>H/<sup>1</sup>H Replacement in DNA

In the present study, the effect of <sup>2</sup>H/<sup>1</sup>H isotopic exchange in hydrogen bonds between nitrogenous base pairs on occurrence and open states zones dynamics is investigated. These processes are studied using mathematical modeling, taking into account the nu...

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Bibliographic Details
Main Authors: Alexander Basov, Mikhail Drobotenko, Alexandr Svidlov, Eugeny Gerasimenko, Vadim Malyshko, Anna Elkina, Mikhail Baryshev, Stepan Dzhimak
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Molecules
Subjects:
deuterium
DNA
mathematical model
open states
rotational movements of nitrogenous bases
dynamics of a double-stranded DNA molecule
Online Access:https://www.mdpi.com/1420-3049/25/16/3753

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