Inflammation as a New Therapeutic Target among Older Patients with Ischemic Heart Disease
Cardiovascular (CV) diseases remain a global health challenge, with ischemic heart disease (IHD) being the primary cause of both morbidity and mortality. Despite optimal pharmacological therapy, older patients with IHD exhibit an increased susceptibility to recurrent ischemic events, significantly i...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-01-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/13/2/363 |
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| author | Daniela Maidana Andrea Arroyo-Álvarez Andrea Arenas-Loriente Guillermo Barreres-Martín Carles Muñoz-Alfonso Daznia Bompart Berroteran Francisca Esteve Claramunt Regina Blanco del Burgo Pedro Cepas-Guillén Sergio Garcia-Blas Clara Bonanad |
| author_facet | Daniela Maidana Andrea Arroyo-Álvarez Andrea Arenas-Loriente Guillermo Barreres-Martín Carles Muñoz-Alfonso Daznia Bompart Berroteran Francisca Esteve Claramunt Regina Blanco del Burgo Pedro Cepas-Guillén Sergio Garcia-Blas Clara Bonanad |
| author_sort | Daniela Maidana |
| collection | DOAJ |
| description | Cardiovascular (CV) diseases remain a global health challenge, with ischemic heart disease (IHD) being the primary cause of both morbidity and mortality. Despite optimal pharmacological therapy, older patients with IHD exhibit an increased susceptibility to recurrent ischemic events, significantly impacting their prognosis. Inflammation is intricately linked with the aging process and plays a pivotal role in the evolution of atherosclerosis. Emerging anti-inflammatory therapies have shown promise in reducing ischemic events among high-risk populations. This review aims to explore the potential of targeted anti-inflammatory interventions in improving clinical outcomes and the quality of life for older patients with IHD. |
| first_indexed | 2024-03-08T09:52:16Z |
| format | Article |
| id | doaj.art-c58ff1c548c44f949e95d7d3cb369adc |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-08T09:52:16Z |
| publishDate | 2024-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-c58ff1c548c44f949e95d7d3cb369adc2024-01-29T14:01:09ZengMDPI AGJournal of Clinical Medicine2077-03832024-01-0113236310.3390/jcm13020363Inflammation as a New Therapeutic Target among Older Patients with Ischemic Heart DiseaseDaniela Maidana0Andrea Arroyo-Álvarez1Andrea Arenas-Loriente2Guillermo Barreres-Martín3Carles Muñoz-Alfonso4Daznia Bompart Berroteran5Francisca Esteve Claramunt6Regina Blanco del Burgo7Pedro Cepas-Guillén8Sergio Garcia-Blas9Clara Bonanad10INCLIVA—Instituto de Investigación Sanitaria, Biomedical Research Institute, 46010 Valencia, SpainINCLIVA—Instituto de Investigación Sanitaria, Biomedical Research Institute, 46010 Valencia, SpainCardiology Department, Hospital Clinic Barcelona, 08036 Barcelona, SpainINCLIVA—Instituto de Investigación Sanitaria, Biomedical Research Institute, 46010 Valencia, SpainINCLIVA—Instituto de Investigación Sanitaria, Biomedical Research Institute, 46010 Valencia, SpainINCLIVA—Instituto de Investigación Sanitaria, Biomedical Research Institute, 46010 Valencia, SpainINCLIVA—Instituto de Investigación Sanitaria, Biomedical Research Institute, 46010 Valencia, SpainINCLIVA—Instituto de Investigación Sanitaria, Biomedical Research Institute, 46010 Valencia, SpainCardiology Department, Hospital Clinic Barcelona, 08036 Barcelona, SpainINCLIVA—Instituto de Investigación Sanitaria, Biomedical Research Institute, 46010 Valencia, SpainINCLIVA—Instituto de Investigación Sanitaria, Biomedical Research Institute, 46010 Valencia, SpainCardiovascular (CV) diseases remain a global health challenge, with ischemic heart disease (IHD) being the primary cause of both morbidity and mortality. Despite optimal pharmacological therapy, older patients with IHD exhibit an increased susceptibility to recurrent ischemic events, significantly impacting their prognosis. Inflammation is intricately linked with the aging process and plays a pivotal role in the evolution of atherosclerosis. Emerging anti-inflammatory therapies have shown promise in reducing ischemic events among high-risk populations. This review aims to explore the potential of targeted anti-inflammatory interventions in improving clinical outcomes and the quality of life for older patients with IHD.https://www.mdpi.com/2077-0383/13/2/363ischemic heart diseaseolder patientsinflammationcardiovascular disease |
| spellingShingle | Daniela Maidana Andrea Arroyo-Álvarez Andrea Arenas-Loriente Guillermo Barreres-Martín Carles Muñoz-Alfonso Daznia Bompart Berroteran Francisca Esteve Claramunt Regina Blanco del Burgo Pedro Cepas-Guillén Sergio Garcia-Blas Clara Bonanad Inflammation as a New Therapeutic Target among Older Patients with Ischemic Heart Disease Journal of Clinical Medicine ischemic heart disease older patients inflammation cardiovascular disease |
| title | Inflammation as a New Therapeutic Target among Older Patients with Ischemic Heart Disease |
| title_full | Inflammation as a New Therapeutic Target among Older Patients with Ischemic Heart Disease |
| title_fullStr | Inflammation as a New Therapeutic Target among Older Patients with Ischemic Heart Disease |
| title_full_unstemmed | Inflammation as a New Therapeutic Target among Older Patients with Ischemic Heart Disease |
| title_short | Inflammation as a New Therapeutic Target among Older Patients with Ischemic Heart Disease |
| title_sort | inflammation as a new therapeutic target among older patients with ischemic heart disease |
| topic | ischemic heart disease older patients inflammation cardiovascular disease |
| url | https://www.mdpi.com/2077-0383/13/2/363 |
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