Primary Localized Amyloidosis of the Bladder Mimicking Neoplasia

A 63-year-old woman was admitted to our hospital with macroscopic hematuria in 2013. On computed tomography, the bladder wall thickness was 2 cm, suspicious for malignancy. Cystoscopy showed irregularity in the posterolateral side of the bladder. Transurethral resection was performed. Histopathologi...

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Bibliographic Details
Main Authors: Sümeyye Ekmekçi, Ülkü Küçük, Ebru Çakır, Emel Ebru Pala, Samir Abdullazade, Özgür Çakmak
Format: Article
Language:English
Published: Galenos Yayinevi 2018-06-01
Series:Journal of Urological Surgery
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Online Access:http://jurolsurgery.org/archives/archive-detail/article-preview/primary-localized-amyloidosis-of-the-bladder-mimic/18507
Description
Summary:A 63-year-old woman was admitted to our hospital with macroscopic hematuria in 2013. On computed tomography, the bladder wall thickness was 2 cm, suspicious for malignancy. Cystoscopy showed irregularity in the posterolateral side of the bladder. Transurethral resection was performed. Histopathological examination revealed a dense homogeneous eosinophilic material in the lamina propria which showed positive orange-red staining with apple-green birefringence under polarized light. There were no signs of systemic amyloidosis at the time of diagnosis and during the 36 months of follow-up. Differential diagnosis of amyloidosis in the bladder includes urothelial carcinoma due to its appearance on imaging and cystoscopy. Histopathological evaluation is a requirement for accurate diagnosis.
ISSN:2148-9580