Mediastinal fibrosis as a late and fatal complication of treated tuberculosis mimicking a neoplastic process in a 34-year-old man
Fibrosing mediastinitis, also known as sclerosing mediastinitis, is an uncommon condition marked by abnormal proliferation of fibrous tissue in the mediastinum. This condition may accrue either as an idiopathic condition or as a complication of an underlying disease process. Its pathogenesis remains...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-12-01
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| Series: | Radiology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043323006386 |
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| author | Manar Ezzahi, MD Zaid Ennasery, MD Sara El Malih, MD Amal Akammar, MD Nizar El Bouardi, MD Meriem Haloua, MD Moulay Youssef Alaoui Lamrani, MD Meryem Boubbou, MD Mounia Serraj, MD Mustapha Maaroufi, MD Mohamed Smahi, MD Amara Bouchra, MD Badreeddine Alami, MD |
| author_facet | Manar Ezzahi, MD Zaid Ennasery, MD Sara El Malih, MD Amal Akammar, MD Nizar El Bouardi, MD Meriem Haloua, MD Moulay Youssef Alaoui Lamrani, MD Meryem Boubbou, MD Mounia Serraj, MD Mustapha Maaroufi, MD Mohamed Smahi, MD Amara Bouchra, MD Badreeddine Alami, MD |
| author_sort | Manar Ezzahi, MD |
| collection | DOAJ |
| description | Fibrosing mediastinitis, also known as sclerosing mediastinitis, is an uncommon condition marked by abnormal proliferation of fibrous tissue in the mediastinum. This condition may accrue either as an idiopathic condition or as a complication of an underlying disease process. Its pathogenesis remains unknown. However, most reported cases are incriminating abnormal immune-mediated hypersensitivity responses to Histoplasma infection. Other rare causes include tuberculosis, blastomycosis, and an idiopathic form that may be associated with other miscellaneous conditions. CT and MR imaging play a vital role in the diagnosis and management of this disease. We present a rare case of fibrosing mediastinitis as a late complication of tuberculosis in a 34-year-old man with a prior history of mediastinal tuberculosis, mimicking initially a neoplastic mediastinal process. We will describe this clinical case in the light of the literature and point out the contribution of radiological imaging in the diagnosis of this rare pathology. |
| first_indexed | 2024-03-11T16:47:34Z |
| format | Article |
| id | doaj.art-c59c41311e2e4013b0f3c45fe949d552 |
| institution | Directory Open Access Journal |
| issn | 1930-0433 |
| language | English |
| last_indexed | 2024-03-11T16:47:34Z |
| publishDate | 2023-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj.art-c59c41311e2e4013b0f3c45fe949d5522023-10-22T04:48:45ZengElsevierRadiology Case Reports1930-04332023-12-01181242874293Mediastinal fibrosis as a late and fatal complication of treated tuberculosis mimicking a neoplastic process in a 34-year-old manManar Ezzahi, MD0Zaid Ennasery, MD1Sara El Malih, MD2Amal Akammar, MD3Nizar El Bouardi, MD4Meriem Haloua, MD5Moulay Youssef Alaoui Lamrani, MD6Meryem Boubbou, MD7Mounia Serraj, MD8Mustapha Maaroufi, MD9Mohamed Smahi, MD10Amara Bouchra, MD11Badreeddine Alami, MD12Department of Radiology and Interventional Imaging, CHU Hassan II Fez, Sidi Mohammed Ben Abdellah University, Fez, Morocco; Corresponding author.Department of Radiology and Interventional Imaging, CHU Hassan II Fez, Sidi Mohammed Ben Abdellah University, Fez, MoroccoDepartment of Radiology and Interventional Imaging, CHU Hassan II Fez, Sidi Mohammed Ben Abdellah University, Fez, MoroccoDepartment of Radiology and Interventional Imaging, CHU Hassan II Fez, Sidi Mohammed Ben Abdellah University, Fez, MoroccoDepartment of Radiology and Interventional Imaging, CHU Hassan II Fez, Sidi Mohammed Ben Abdellah University, Fez, MoroccoDepartment of Radiology and Interventional Imaging, CHU Hassan II Fez, Sidi Mohammed Ben Abdellah University, Fez, MoroccoDepartment of Radiology and Interventional Imaging, CHU Hassan II Fez, Sidi Mohammed Ben Abdellah University, Fez, MoroccoDepartment of Radiology and Interventional Imaging, CHU Hassan II Fez, Sidi Mohammed Ben Abdellah University, Fez, MoroccoDepartment of Pneumology - CHU Hassan II Fez, Sidi Mohammed Ben Abdellah University, Fez, MoroccoDepartment of Radiology and Interventional Imaging, CHU Hassan II Fez, Sidi Mohammed Ben Abdellah University, Fez, MoroccoDepartment of Thoracic Surgery - CHU Hassan II Fez, Sidi Mohammed Ben Abdellah University, Fez, MoroccoDepartment of Pneumology - CHU Hassan II Fez, Sidi Mohammed Ben Abdellah University, Fez, MoroccoDepartment of Radiology and Interventional Imaging, CHU Hassan II Fez, Sidi Mohammed Ben Abdellah University, Fez, MoroccoFibrosing mediastinitis, also known as sclerosing mediastinitis, is an uncommon condition marked by abnormal proliferation of fibrous tissue in the mediastinum. This condition may accrue either as an idiopathic condition or as a complication of an underlying disease process. Its pathogenesis remains unknown. However, most reported cases are incriminating abnormal immune-mediated hypersensitivity responses to Histoplasma infection. Other rare causes include tuberculosis, blastomycosis, and an idiopathic form that may be associated with other miscellaneous conditions. CT and MR imaging play a vital role in the diagnosis and management of this disease. We present a rare case of fibrosing mediastinitis as a late complication of tuberculosis in a 34-year-old man with a prior history of mediastinal tuberculosis, mimicking initially a neoplastic mediastinal process. We will describe this clinical case in the light of the literature and point out the contribution of radiological imaging in the diagnosis of this rare pathology.http://www.sciencedirect.com/science/article/pii/S1930043323006386FibrosisMediastinalTuberculosisCTMRI |
| spellingShingle | Manar Ezzahi, MD Zaid Ennasery, MD Sara El Malih, MD Amal Akammar, MD Nizar El Bouardi, MD Meriem Haloua, MD Moulay Youssef Alaoui Lamrani, MD Meryem Boubbou, MD Mounia Serraj, MD Mustapha Maaroufi, MD Mohamed Smahi, MD Amara Bouchra, MD Badreeddine Alami, MD Mediastinal fibrosis as a late and fatal complication of treated tuberculosis mimicking a neoplastic process in a 34-year-old man Radiology Case Reports Fibrosis Mediastinal Tuberculosis CT MRI |
| title | Mediastinal fibrosis as a late and fatal complication of treated tuberculosis mimicking a neoplastic process in a 34-year-old man |
| title_full | Mediastinal fibrosis as a late and fatal complication of treated tuberculosis mimicking a neoplastic process in a 34-year-old man |
| title_fullStr | Mediastinal fibrosis as a late and fatal complication of treated tuberculosis mimicking a neoplastic process in a 34-year-old man |
| title_full_unstemmed | Mediastinal fibrosis as a late and fatal complication of treated tuberculosis mimicking a neoplastic process in a 34-year-old man |
| title_short | Mediastinal fibrosis as a late and fatal complication of treated tuberculosis mimicking a neoplastic process in a 34-year-old man |
| title_sort | mediastinal fibrosis as a late and fatal complication of treated tuberculosis mimicking a neoplastic process in a 34 year old man |
| topic | Fibrosis Mediastinal Tuberculosis CT MRI |
| url | http://www.sciencedirect.com/science/article/pii/S1930043323006386 |
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