Unanesthetized Rodents Demonstrate Insensitivity of QT Interval and Ventricular Refractory Period to Pacing Cycle Length

Unanesthetized Rodents Demonstrate Insensitivity of QT Interval and Ventricular Refractory Period to Pacing Cycle Length

Aim: The cardiac electrophysiology of mice and rats has been analyzed extensively, often in the context of pathological manipulations. However, the effects of beating rate on the basic electrical properties of the rodent heart remain unclear. Due to technical challenges, reported electrophysiologica...

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Bibliographic Details
Main Authors: Wesam Mulla, Roni Gillis, Michael Murninkas, Hadar Klapper-Goldstein, Hovav Gabay, Michal Mor, Sigal Elyagon, Noah Liel-Cohen, Olivier Bernus, Yoram Etzion
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Physiology
Subjects:
ECG
effective refractory period
monophasic action potential
rate-adaptation
rodent cardiac electrophysiology
QT interval
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.00897/full

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