Extracellular acidosis suppresses calcification of vascular smooth muscle cells by inhibiting calcium influx via L-type calcium channels

Extracellular acidosis suppresses calcification of vascular smooth muscle cells by inhibiting calcium influx via L-type calcium channels

Vascular calcification such as arteriosclerosis, which is characterized by a calcification of the tunica media, is a severe complication of chronic kidney disease (CKD), contributing to the high prevalence of cardiovascular morbidity and mortality in patients with CKD. An essential step during the d...

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Bibliographic Details
Main Authors: Shenglei Zhang, Jinsheng Xu, Yu Feng, Junxia Zhang, Liwen Cui, Huiran Zhang, Yaling Bai
Format: Article
Language:English
Published: Taylor & Francis Group 2018-05-01
Series:Clinical and Experimental Hypertension
Subjects:
vascular smooth muscle cells
β-glycerophosphate
acidosis
calcification
l-type calcium channel
runx2
chronic kidney disease
Online Access:http://dx.doi.org/10.1080/10641963.2017.1384482

Internet

http://dx.doi.org/10.1080/10641963.2017.1384482

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