<i>ICOS</i> gene polymorphisms in B-cell chronic lymphocytic leukemia in the Polish population

<i>ICOS</i> gene polymorphisms in B-cell chronic lymphocytic leukemia in the Polish population

There is strong evidence that altered immunological function entails an increased risk of B-cell chronic lymphocytic leukemia (B-CLL). The main mechanism of an anti-tumor response depends on T-cell activation. Unlike the constitutively expressed CD28, inducible costimulatory molecule (ICOS) is expre...

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Bibliographic Details
Main Authors:	Irena Frydecka, Kazimierz Kuliczkowski, Dariusz Woszczyk, Marek Kielbinski, Dariusz Wolowiec, Anna Tomkiewicz, Anna Jedynak, Lidia Karabon
Format:	Article
Language:	English
Published:	Via Medica 2011-04-01
Series:	Folia Histochemica et Cytobiologica
Subjects:	ICOS polymorphisms B-CLL
Online Access:	http://czasopisma.viamedica.pl/fhc/article/view/4143

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