Individual odor hedonic perception is coded in temporal joint network activity
Intro: The human sense of smell is highly individual and characterized by a strong variability in the perception and evaluation of olfactory stimuli, depending on cultural imprint and current physiological conditions. Since this individual perspective has often been neglected in fMRI studies on olfa...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-04-01
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| Series: | NeuroImage |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1053811921000598 |
| _version_ | 1818443491436396544 |
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| author | Paul Ruser Carina J. Koeppel Hagen H. Kitzler Thomas Hummel Ilona Croy |
| author_facet | Paul Ruser Carina J. Koeppel Hagen H. Kitzler Thomas Hummel Ilona Croy |
| author_sort | Paul Ruser |
| collection | DOAJ |
| description | Intro: The human sense of smell is highly individual and characterized by a strong variability in the perception and evaluation of olfactory stimuli, depending on cultural imprint and current physiological conditions. Since this individual perspective has often been neglected in fMRI studies on olfactory hedonic coding, this study focuses on the neuronal activity and connectivity patterns resulting from subject-specific olfactory stimulation. Methods: : Thirty-one normosmic participants took part in a fMRI block designed paradigm consisting of three olfactory stimulation sessions. The most pleasant and unpleasant odors were individually specified during a pre-test for each participant and validated in the main experiment. Mean activation and functional connectivity analysis focusing on the right and left piriform cortex were performed for the predefined olfactory regions-of-interest (ROIs) and compared between the three olfactory conditions. Results: : Individual unpleasant olfactory stimulation as compared to pleasant or neutral did not alter mean BOLD activation in the predefined olfactory ROIs but led to a change in connectivity pattern in the right piriform cortex. Conclusion: : Our data suggests that the individual pleasantness of odors is not detectable by average BOLD magnitude changes in primary or secondary olfactory brain areas, but reflected in temporal patterns of joint activation that create a network between the right piriform cortex, the left insular cortex, the orbitofrontal cortex, and the precentral gyrus. This network may serve the evolutionary defense mechanism of olfaction by preparing goal-directed action. |
| first_indexed | 2024-12-14T19:00:53Z |
| format | Article |
| id | doaj.art-c5a291f6205649aeb1404c0e2ee45816 |
| institution | Directory Open Access Journal |
| issn | 1095-9572 |
| language | English |
| last_indexed | 2024-12-14T19:00:53Z |
| publishDate | 2021-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | NeuroImage |
| spelling | doaj.art-c5a291f6205649aeb1404c0e2ee458162022-12-21T22:50:57ZengElsevierNeuroImage1095-95722021-04-01229117782Individual odor hedonic perception is coded in temporal joint network activityPaul Ruser0Carina J. Koeppel1Hagen H. Kitzler2Thomas Hummel3Ilona Croy4Department of Psychotherapy and Psychosomatic Medicine, TU Dresden Faculty of Medicine Carl Gustav Carus, Dresden, GermanyDepartment of Psychotherapy and Psychosomatic Medicine, TU Dresden Faculty of Medicine Carl Gustav Carus, Dresden, GermanyClinic for Diagnostic and Interventional Neuroradiology, TU Dresden Faculty of Medicine Carl Gustav Carus, Dresden, GermanySmell & Taste Clinic, Department of Otorhinolaryngology, TU Dresden Faculty of Medicine Carl Gustav Carus, Dresden, GermanyDepartment of Psychotherapy and Psychosomatic Medicine, TU Dresden Faculty of Medicine Carl Gustav Carus, Dresden, Germany; Department of Psychology, Friedrich Schiller University of Jena, Germany; Corresponding author.Intro: The human sense of smell is highly individual and characterized by a strong variability in the perception and evaluation of olfactory stimuli, depending on cultural imprint and current physiological conditions. Since this individual perspective has often been neglected in fMRI studies on olfactory hedonic coding, this study focuses on the neuronal activity and connectivity patterns resulting from subject-specific olfactory stimulation. Methods: : Thirty-one normosmic participants took part in a fMRI block designed paradigm consisting of three olfactory stimulation sessions. The most pleasant and unpleasant odors were individually specified during a pre-test for each participant and validated in the main experiment. Mean activation and functional connectivity analysis focusing on the right and left piriform cortex were performed for the predefined olfactory regions-of-interest (ROIs) and compared between the three olfactory conditions. Results: : Individual unpleasant olfactory stimulation as compared to pleasant or neutral did not alter mean BOLD activation in the predefined olfactory ROIs but led to a change in connectivity pattern in the right piriform cortex. Conclusion: : Our data suggests that the individual pleasantness of odors is not detectable by average BOLD magnitude changes in primary or secondary olfactory brain areas, but reflected in temporal patterns of joint activation that create a network between the right piriform cortex, the left insular cortex, the orbitofrontal cortex, and the precentral gyrus. This network may serve the evolutionary defense mechanism of olfaction by preparing goal-directed action.http://www.sciencedirect.com/science/article/pii/S1053811921000598OlfactionBehavioral immune systemFunctional connectivity analysis |
| spellingShingle | Paul Ruser Carina J. Koeppel Hagen H. Kitzler Thomas Hummel Ilona Croy Individual odor hedonic perception is coded in temporal joint network activity NeuroImage Olfaction Behavioral immune system Functional connectivity analysis |
| title | Individual odor hedonic perception is coded in temporal joint network activity |
| title_full | Individual odor hedonic perception is coded in temporal joint network activity |
| title_fullStr | Individual odor hedonic perception is coded in temporal joint network activity |
| title_full_unstemmed | Individual odor hedonic perception is coded in temporal joint network activity |
| title_short | Individual odor hedonic perception is coded in temporal joint network activity |
| title_sort | individual odor hedonic perception is coded in temporal joint network activity |
| topic | Olfaction Behavioral immune system Functional connectivity analysis |
| url | http://www.sciencedirect.com/science/article/pii/S1053811921000598 |
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