Research progress on the role of DNA methylation in the occurrence and prognosis of lung cancer
Lung cancer is a leading cause of cancer-related morbidity and mortality in China. Early recurrence is the main cause of poor prognosis. The existing prognostic indicators are insufficient. Thus, it is urgent to find reliable prognostic indicators. DNA methylation is the most important epigenetic ch...
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| Format: | Article |
| Language: | zho |
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Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.
2023-03-01
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| Series: | Jichu yixue yu linchuang |
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| Online Access: | http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2023-43-3-514.pdf |
| _version_ | 1797366382028914688 |
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| author | XUE Jianchao, WANG Yadong, LI Bowen, LIU Xinyu, LIANG Naixin, LI Shanqing |
| author_facet | XUE Jianchao, WANG Yadong, LI Bowen, LIU Xinyu, LIANG Naixin, LI Shanqing |
| author_sort | XUE Jianchao, WANG Yadong, LI Bowen, LIU Xinyu, LIANG Naixin, LI Shanqing |
| collection | DOAJ |
| description | Lung cancer is a leading cause of cancer-related morbidity and mortality in China. Early recurrence is the main cause of poor prognosis. The existing prognostic indicators are insufficient. Thus, it is urgent to find reliable prognostic indicators. DNA methylation is the most important epigenetic change in the development of lung cancer. With the development of high-throughput sequencing technology, DNA methylation has shown its great clinical value in the prognosis prediction of lung cancer patients due to its stable and detectable features. |
| first_indexed | 2024-03-08T17:03:22Z |
| format | Article |
| id | doaj.art-c5a7d400710d48edbe5e522f3f4448bf |
| institution | Directory Open Access Journal |
| issn | 1001-6325 |
| language | zho |
| last_indexed | 2024-03-08T17:03:22Z |
| publishDate | 2023-03-01 |
| publisher | Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. |
| record_format | Article |
| series | Jichu yixue yu linchuang |
| spelling | doaj.art-c5a7d400710d48edbe5e522f3f4448bf2024-01-04T07:27:31ZzhoInstitute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.Jichu yixue yu linchuang1001-63252023-03-0143351451810.16352/j.issn.1001-6325.2023.03.514Research progress on the role of DNA methylation in the occurrence and prognosis of lung cancerXUE Jianchao, WANG Yadong, LI Bowen, LIU Xinyu, LIANG Naixin, LI Shanqing01. Department of Thoracic Surgery, Peking Union Medical College Hospital, CAMS & PUMC, Beijing 100730;;2. Grade 2016, Eight-year Program of Clinical Medicine, PUMC, Beijing 100730, ChinaLung cancer is a leading cause of cancer-related morbidity and mortality in China. Early recurrence is the main cause of poor prognosis. The existing prognostic indicators are insufficient. Thus, it is urgent to find reliable prognostic indicators. DNA methylation is the most important epigenetic change in the development of lung cancer. With the development of high-throughput sequencing technology, DNA methylation has shown its great clinical value in the prognosis prediction of lung cancer patients due to its stable and detectable features.http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2023-43-3-514.pdflung cancer|dna methylation|prognosis|epigenetics |
| spellingShingle | XUE Jianchao, WANG Yadong, LI Bowen, LIU Xinyu, LIANG Naixin, LI Shanqing Research progress on the role of DNA methylation in the occurrence and prognosis of lung cancer Jichu yixue yu linchuang lung cancer|dna methylation|prognosis|epigenetics |
| title | Research progress on the role of DNA methylation in the occurrence and prognosis of lung cancer |
| title_full | Research progress on the role of DNA methylation in the occurrence and prognosis of lung cancer |
| title_fullStr | Research progress on the role of DNA methylation in the occurrence and prognosis of lung cancer |
| title_full_unstemmed | Research progress on the role of DNA methylation in the occurrence and prognosis of lung cancer |
| title_short | Research progress on the role of DNA methylation in the occurrence and prognosis of lung cancer |
| title_sort | research progress on the role of dna methylation in the occurrence and prognosis of lung cancer |
| topic | lung cancer|dna methylation|prognosis|epigenetics |
| url | http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2023-43-3-514.pdf |
| work_keys_str_mv | AT xuejianchaowangyadonglibowenliuxinyuliangnaixinlishanqing researchprogressontheroleofdnamethylationintheoccurrenceandprognosisoflungcancer |