Invasive bladder cancer in the eighties: transurethral resection or cystectomy?

PURPOSE: Describe morbidity and survival in patients older than 80 years with muscle invasive bladder cancer (MIBC) treated with radical cystectomy (RC) or transurethral resection (TUR) in our institution. MATERIALS AND METHODS: We reviewed our database of all patients older than 80 years treated wi...

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Main Authors: Oscar Rodriguez Faba, Joan Palou, Guillermo Urdaneta, Luis Gausa, Humberto Villavicencio
Format: Article
Language:English
Published: Sociedade Brasileira de Urologia 2011-02-01
Series:International Brazilian Journal of Urology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382011000100007
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author Oscar Rodriguez Faba
Joan Palou
Guillermo Urdaneta
Luis Gausa
Humberto Villavicencio
author_facet Oscar Rodriguez Faba
Joan Palou
Guillermo Urdaneta
Luis Gausa
Humberto Villavicencio
author_sort Oscar Rodriguez Faba
collection DOAJ
description PURPOSE: Describe morbidity and survival in patients older than 80 years with muscle invasive bladder cancer (MIBC) treated with radical cystectomy (RC) or transurethral resection (TUR) in our institution. MATERIALS AND METHODS: We reviewed our database of all patients older than 80 years treated with RC and TUR for MIBC between 1993 and 2005 in our institution. Twenty-seven patients were submitted to RC, with mean age of 82 years and mean follow-up of 16.4 months. RC was carried out following diagnosis of previous MIBC in 14 cases (51.9%). The American Society of Anesthesiology (ASA) score was III or IV in 23 patients (85.1%). Seventy-two patients with a mean age of 84 years and mean follow-up of 33 months, diagnosed with MIBC, were managed by means of TUR. The ASA score was III-IV in 64 (88.8%) patients. RESULTS: Pathological stage of the RC specimen was pT3 in 18 cases (66.7%). Mean hospital stay was 16 days. Early complications were assessed in 8 patients (29.6%), with an overall survival (OS) of 42.94%, and cancer-specific survival (CSS) of 60.54%. In patients submitted to TUR, clinical stage was T2 in 36 cases (50%). The mean hospital stay was 7 days, with a readmission rate (RR) of 87.5%. OS and CSS was less than 20%. CONCLUSIONS: RC in octogenarian patients is a safe procedure, with complication and survival rates comparable to RC series in general population. Transurethral resection (TUR) for patients with MIBC within this age range is a much less morbid procedure, but disease specific survival is lower.
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spelling doaj.art-c5a8c12649c748a69aeec83bd9a68e592022-12-21T22:27:28ZengSociedade Brasileira de UrologiaInternational Brazilian Journal of Urology1677-55381677-61192011-02-01371495610.1590/S1677-55382011000100007Invasive bladder cancer in the eighties: transurethral resection or cystectomy?Oscar Rodriguez FabaJoan PalouGuillermo UrdanetaLuis GausaHumberto VillavicencioPURPOSE: Describe morbidity and survival in patients older than 80 years with muscle invasive bladder cancer (MIBC) treated with radical cystectomy (RC) or transurethral resection (TUR) in our institution. MATERIALS AND METHODS: We reviewed our database of all patients older than 80 years treated with RC and TUR for MIBC between 1993 and 2005 in our institution. Twenty-seven patients were submitted to RC, with mean age of 82 years and mean follow-up of 16.4 months. RC was carried out following diagnosis of previous MIBC in 14 cases (51.9%). The American Society of Anesthesiology (ASA) score was III or IV in 23 patients (85.1%). Seventy-two patients with a mean age of 84 years and mean follow-up of 33 months, diagnosed with MIBC, were managed by means of TUR. The ASA score was III-IV in 64 (88.8%) patients. RESULTS: Pathological stage of the RC specimen was pT3 in 18 cases (66.7%). Mean hospital stay was 16 days. Early complications were assessed in 8 patients (29.6%), with an overall survival (OS) of 42.94%, and cancer-specific survival (CSS) of 60.54%. In patients submitted to TUR, clinical stage was T2 in 36 cases (50%). The mean hospital stay was 7 days, with a readmission rate (RR) of 87.5%. OS and CSS was less than 20%. CONCLUSIONS: RC in octogenarian patients is a safe procedure, with complication and survival rates comparable to RC series in general population. Transurethral resection (TUR) for patients with MIBC within this age range is a much less morbid procedure, but disease specific survival is lower.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382011000100007urinary bladder neoplasmscystectomyendoscopyaged
spellingShingle Oscar Rodriguez Faba
Joan Palou
Guillermo Urdaneta
Luis Gausa
Humberto Villavicencio
Invasive bladder cancer in the eighties: transurethral resection or cystectomy?
International Brazilian Journal of Urology
urinary bladder neoplasms
cystectomy
endoscopy
aged
title Invasive bladder cancer in the eighties: transurethral resection or cystectomy?
title_full Invasive bladder cancer in the eighties: transurethral resection or cystectomy?
title_fullStr Invasive bladder cancer in the eighties: transurethral resection or cystectomy?
title_full_unstemmed Invasive bladder cancer in the eighties: transurethral resection or cystectomy?
title_short Invasive bladder cancer in the eighties: transurethral resection or cystectomy?
title_sort invasive bladder cancer in the eighties transurethral resection or cystectomy
topic urinary bladder neoplasms
cystectomy
endoscopy
aged
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382011000100007
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AT guillermourdaneta invasivebladdercancerintheeightiestransurethralresectionorcystectomy
AT luisgausa invasivebladdercancerintheeightiestransurethralresectionorcystectomy
AT humbertovillavicencio invasivebladdercancerintheeightiestransurethralresectionorcystectomy