Combined effect of CCND1 and COMT polymorphisms and increased breast cancer risk

Combined effect of CCND1 and COMT polymorphisms and increased breast cancer risk

<p>Abstract</p> <p>Background</p> <p>Estrogens are crucial tumorigenic hormones, which impact the cell growth and proliferation during breast cancer development. Estrogens are metabolized by a series of enzymes including COMT, which converts catechol estrogens into biol...

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Main Authors: Knight Julia A, Briollais Laurent, Aaltonen Kirsimari, Onay Ummiye V, Pabalan Noel, Kilpivaara Outi, Andrulis Irene L, Blomqvist Carl, Nevanlinna Heli, Ozcelik Hilmi
Format: Article
Language:English
Published: BMC 2008-01-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/8/6

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