Narrowband Ultraviolet B (NB-UVB) Phototherapy in Psoriasis: A Retrospective Study
Background: Psoriasis with higher Psoriasis Area and Severity Index (PASI) scores correlate with impaired quality of life. Assessing narrowband ultraviolet B (NB-UVB) phototherapy as a new therapy option in Indonesia is necessary to find the most effective treatment for psoriasis patients. Purpose:...
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| Format: | Article |
| Language: | Indonesian |
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Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga
2022-07-01
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| Series: | Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology) |
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| Online Access: | https://e-journal.unair.ac.id/BIKK/article/view/32740 |
| _version_ | 1797506054030884864 |
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| author | Faida Ufaira Prameswari Widiana Ferriastuti |
| author_facet | Faida Ufaira Prameswari Widiana Ferriastuti |
| author_sort | Faida Ufaira Prameswari |
| collection | DOAJ |
| description | Background: Psoriasis with higher Psoriasis Area and Severity Index (PASI) scores correlate with impaired quality of life. Assessing narrowband ultraviolet B (NB-UVB) phototherapy as a new therapy option in Indonesia is necessary to find the most effective treatment for psoriasis patients. Purpose: To determine the usage of NB-UVB phototherapy and the therapy response in psoriasis patients. Methods: This retrospective descriptive observational study was conducted at Dr. Soetomo General Academic Hospital Surabaya in March 2019-November 2020. The variables were collected through medical records. Result: A total of 28 patients were obtained at this study. Psoriasis type plaque/vulgaris were found in 92.9% of the patients. The patients mostly started with PASI score >10 with the initial dose of NB-UVB phototherapy is 260 mJ/cm2. The most common initial phototherapy frequency is 3 times per week (53.6%). The latest dose and frequency distribution was varied in each subject. The mean total number of sessions was 31.54 ± 20.549. Patients were also administered various combination therapy. The majority of patients had missed NB-UVB phototherapy sessions and the phototherapy dose needed to be reduced (57.1%). The achievement of PASI-75 (treatment success) was mostly achieved by subjects that went through 40-60 sessions of phototherapy and subjects with psoriasis type plaque/vulgaris. Conclusion: The achievement of PASI-75 was found to be low (17.5%), influenced by multiple factors such as the total number of NB-UVB phototherapy sessions, combination therapy, dose of NB-UVB phototherapy, frequency of NB-UVB phototherapy, and the level of patient compliance to therapy. |
| first_indexed | 2024-03-10T04:27:07Z |
| format | Article |
| id | doaj.art-c5ab70fdac594aa190e933fa0c34e3c7 |
| institution | Directory Open Access Journal |
| issn | 1978-4279 2549-4082 |
| language | Indonesian |
| last_indexed | 2024-03-10T04:27:07Z |
| publishDate | 2022-07-01 |
| publisher | Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga |
| record_format | Article |
| series | Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology) |
| spelling | doaj.art-c5ab70fdac594aa190e933fa0c34e3c72023-11-23T06:35:52ZindDepartment of Dermatology and Venereology, Faculty of Medicine, Universitas AirlanggaBerkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology)1978-42792549-40822022-07-013429910810.20473/bikk.V34.2.2022.99-10826853Narrowband Ultraviolet B (NB-UVB) Phototherapy in Psoriasis: A Retrospective StudyFaida Ufaira Prameswari0https://orcid.org/0000-0002-2398-6760Widiana Ferriastuti1Medical Program, Faculty of Medicine, Universitas Airlangga, Surabaya, IndonesiaDepartment of Radiology, Faculty of Medicine Universitas Airlangga/Dr. Soetomo General Academic Hospital, Surabaya, IndonesiaBackground: Psoriasis with higher Psoriasis Area and Severity Index (PASI) scores correlate with impaired quality of life. Assessing narrowband ultraviolet B (NB-UVB) phototherapy as a new therapy option in Indonesia is necessary to find the most effective treatment for psoriasis patients. Purpose: To determine the usage of NB-UVB phototherapy and the therapy response in psoriasis patients. Methods: This retrospective descriptive observational study was conducted at Dr. Soetomo General Academic Hospital Surabaya in March 2019-November 2020. The variables were collected through medical records. Result: A total of 28 patients were obtained at this study. Psoriasis type plaque/vulgaris were found in 92.9% of the patients. The patients mostly started with PASI score >10 with the initial dose of NB-UVB phototherapy is 260 mJ/cm2. The most common initial phototherapy frequency is 3 times per week (53.6%). The latest dose and frequency distribution was varied in each subject. The mean total number of sessions was 31.54 ± 20.549. Patients were also administered various combination therapy. The majority of patients had missed NB-UVB phototherapy sessions and the phototherapy dose needed to be reduced (57.1%). The achievement of PASI-75 (treatment success) was mostly achieved by subjects that went through 40-60 sessions of phototherapy and subjects with psoriasis type plaque/vulgaris. Conclusion: The achievement of PASI-75 was found to be low (17.5%), influenced by multiple factors such as the total number of NB-UVB phototherapy sessions, combination therapy, dose of NB-UVB phototherapy, frequency of NB-UVB phototherapy, and the level of patient compliance to therapy.https://e-journal.unair.ac.id/BIKK/article/view/32740psoriasisphototherapynb-uvbpasihuman and disease |
| spellingShingle | Faida Ufaira Prameswari Widiana Ferriastuti Narrowband Ultraviolet B (NB-UVB) Phototherapy in Psoriasis: A Retrospective Study Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology) psoriasis phototherapy nb-uvb pasi human and disease |
| title | Narrowband Ultraviolet B (NB-UVB) Phototherapy in Psoriasis: A Retrospective Study |
| title_full | Narrowband Ultraviolet B (NB-UVB) Phototherapy in Psoriasis: A Retrospective Study |
| title_fullStr | Narrowband Ultraviolet B (NB-UVB) Phototherapy in Psoriasis: A Retrospective Study |
| title_full_unstemmed | Narrowband Ultraviolet B (NB-UVB) Phototherapy in Psoriasis: A Retrospective Study |
| title_short | Narrowband Ultraviolet B (NB-UVB) Phototherapy in Psoriasis: A Retrospective Study |
| title_sort | narrowband ultraviolet b nb uvb phototherapy in psoriasis a retrospective study |
| topic | psoriasis phototherapy nb-uvb pasi human and disease |
| url | https://e-journal.unair.ac.id/BIKK/article/view/32740 |
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