Pre- and Post-Race Intestinal Microbiota in Long-Distance Sled Dogs and Associations with Performance
Although our understanding of the role of the gut microbiota in different diseases is improving, our knowledge regarding how the gut microbiota affects functioning in healthy individuals is still limited. Here, we hypothesize that the gut microbiota could be associated with sled dog endurance-race p...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-01-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/10/2/204 |
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| author | Kristoffer Relling Tysnes Inga Leena Angell Iselin Fjellanger Sigrid Drageset Larsen Silje Rebekka Søfteland Lucy J. Robertson Ellen Skancke Knut Rudi |
| author_facet | Kristoffer Relling Tysnes Inga Leena Angell Iselin Fjellanger Sigrid Drageset Larsen Silje Rebekka Søfteland Lucy J. Robertson Ellen Skancke Knut Rudi |
| author_sort | Kristoffer Relling Tysnes |
| collection | DOAJ |
| description | Although our understanding of the role of the gut microbiota in different diseases is improving, our knowledge regarding how the gut microbiota affects functioning in healthy individuals is still limited. Here, we hypothesize that the gut microbiota could be associated with sled dog endurance-race performance. We investigated the gut microbiota in 166 fecal samples from 96 Alaskan Huskies, representing 16 teams participating in the 2016 Femund Race (400 km) in Norway, relating the microbiota composition to performance and metadata derived from questionnaires. For 16S rRNA gene sequencing-derived compositional data, we found a strong negative association between <i>Enterobacteriaceae</i> (dysbiosis-associated) and <i>Clostridium hiranonis</i> (normobiosis-associated). The teams with the best performances showed both the lowest levels of dysbiosis-associated bacteria prior to the race and the lowest change (decrease) in these bacteria after the race. Taken together, our results support the hypothesis that normobiosis-associated bacteria are involved in resilience mechanisms, potentially preventing growth of <i>Enterobacteriaceae</i> during the race. |
| first_indexed | 2024-12-14T21:40:12Z |
| format | Article |
| id | doaj.art-c5abc20945ff4d999c279372c2ec4b83 |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-12-14T21:40:12Z |
| publishDate | 2020-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-c5abc20945ff4d999c279372c2ec4b832022-12-21T22:46:29ZengMDPI AGAnimals2076-26152020-01-0110220410.3390/ani10020204ani10020204Pre- and Post-Race Intestinal Microbiota in Long-Distance Sled Dogs and Associations with PerformanceKristoffer Relling Tysnes0Inga Leena Angell1Iselin Fjellanger2Sigrid Drageset Larsen3Silje Rebekka Søfteland4Lucy J. Robertson5Ellen Skancke6Knut Rudi7Department of Paraclinical Sciences, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, P.B. 369 Sentrum, 0102 Oslo, NorwayDepartment of Chemistry, Biotechnology and Food science (IKBM), Norwegian University of Life Sciences, 1430, Box 5003 Ås, NorwayDepartment of Paraclinical Sciences, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, P.B. 369 Sentrum, 0102 Oslo, NorwayDepartment of Paraclinical Sciences, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, P.B. 369 Sentrum, 0102 Oslo, NorwayDepartment of Paraclinical Sciences, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, P.B. 369 Sentrum, 0102 Oslo, NorwayDepartment of Paraclinical Sciences, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, P.B. 369 Sentrum, 0102 Oslo, NorwayDepartment of Companion Animal Clinical Sciences (SportFaMed), Faculty of Veterinary Medicine, Norwegian University of Life Sciences, 0102 Oslo, NorwayDepartment of Chemistry, Biotechnology and Food science (IKBM), Norwegian University of Life Sciences, 1430, Box 5003 Ås, NorwayAlthough our understanding of the role of the gut microbiota in different diseases is improving, our knowledge regarding how the gut microbiota affects functioning in healthy individuals is still limited. Here, we hypothesize that the gut microbiota could be associated with sled dog endurance-race performance. We investigated the gut microbiota in 166 fecal samples from 96 Alaskan Huskies, representing 16 teams participating in the 2016 Femund Race (400 km) in Norway, relating the microbiota composition to performance and metadata derived from questionnaires. For 16S rRNA gene sequencing-derived compositional data, we found a strong negative association between <i>Enterobacteriaceae</i> (dysbiosis-associated) and <i>Clostridium hiranonis</i> (normobiosis-associated). The teams with the best performances showed both the lowest levels of dysbiosis-associated bacteria prior to the race and the lowest change (decrease) in these bacteria after the race. Taken together, our results support the hypothesis that normobiosis-associated bacteria are involved in resilience mechanisms, potentially preventing growth of <i>Enterobacteriaceae</i> during the race.https://www.mdpi.com/2076-2615/10/2/204sled dogmicrobiotadysbiosis16s rrna gene |
| spellingShingle | Kristoffer Relling Tysnes Inga Leena Angell Iselin Fjellanger Sigrid Drageset Larsen Silje Rebekka Søfteland Lucy J. Robertson Ellen Skancke Knut Rudi Pre- and Post-Race Intestinal Microbiota in Long-Distance Sled Dogs and Associations with Performance Animals sled dog microbiota dysbiosis 16s rrna gene |
| title | Pre- and Post-Race Intestinal Microbiota in Long-Distance Sled Dogs and Associations with Performance |
| title_full | Pre- and Post-Race Intestinal Microbiota in Long-Distance Sled Dogs and Associations with Performance |
| title_fullStr | Pre- and Post-Race Intestinal Microbiota in Long-Distance Sled Dogs and Associations with Performance |
| title_full_unstemmed | Pre- and Post-Race Intestinal Microbiota in Long-Distance Sled Dogs and Associations with Performance |
| title_short | Pre- and Post-Race Intestinal Microbiota in Long-Distance Sled Dogs and Associations with Performance |
| title_sort | pre and post race intestinal microbiota in long distance sled dogs and associations with performance |
| topic | sled dog microbiota dysbiosis 16s rrna gene |
| url | https://www.mdpi.com/2076-2615/10/2/204 |
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